Abstract：
During secondary alveolar cleft grafting, the use of autogenous cancellous bone harvested from the iliac crest is still considered the gold standard. Due to the risk of donor-site morbidity and excessive graft resorption, alternative grafting materials (e.g. intraoral bone, xenografts) have been tested. Autogenous tooth bone graft (ATB) is a novel material derived from extracted teeth. ATB has successfully been used in pre-prosthetic and periodontal surgery for hard-tissue reconstruction. Seven patients with unilateral cleft lip and palate were treated with ATB, using their own deciduous teeth for grafting. Defects were accessed utilizing a novel split-thickness papilla curtain flap. Cone-beam computed tomography scans were taken prior to and 3 months following cleft surgery to assess graft integration, graft stability, and the volume of the newly formed hard tissues. Hard-tissue gain, as measured at the 3-month follow-up, averaged 0.65 cm3 ± 0.26 cm3. Results showed acceptable graft integration and stability at the 3-month follow-up, with no adverse effects or excessive resorption of the graft. The use of ATB might be a feasible alternative for alveolar cleft grafting. However, long-term studies using a large sample size are required to derive further conclusions.
摘要：
在继发性肺泡裂隙移植期间，使用自体松质骨从髂骨收获仍然被认为是金标准。由于供体部位发病和过度移植物吸收的风险，替代移植材料(如口内骨，异种移植物）已经过测试。自体牙骨移植（ATB）是一种源自拔牙的新型材料。ATB已成功用于修复前和牙周手术中的硬组织重建。7例单侧唇腭裂患者接受ATB治疗，用自己的乳牙进行移植。使用一种新颖的厚度分裂的乳头窗帘瓣来获取缺陷。在裂隙手术之前和术后3个月进行锥形束计算机断层扫描，以评估移植物的整合。移植物稳定性，和新形成的硬组织的体积。硬组织增益,在3个月的随访中测量，平均0.65cm3±0.26cm3。结果表明，在3个月的随访中，移植物整合和稳定性可接受，没有副作用或移植物的过度吸收。使用ATB可能是肺泡裂隙移植的可行替代方法。然而,需要使用大样本量的长期研究才能得出进一步的结论。
