Abstract:
Ewing sarcoma is the most common malignant bone tumor of the pelvis in children and young adults. Even with aggressive treatment, its survival rate is amongst the poorest. Classical presentation may not be the rule. It may simulate clinically, imagiologically and histopathologically other nonmalignant entities. Therefore, its suspicion should not be overlooked. We report two cases of pelvic Ewing sarcoma: the first mimicking eosinophilic granuloma, and the second mimicking osteomyelitis. In the latter, we also report an atypical finding of its natural history: an initial response to antibiotic and anti-inflammatory treatment. In both cases, we highlight the possibility of an inconclusive percutaneous bone biopsy and the importance of immunochemistry and cytogenetics for the definitive diagnosis.
摘要:
尤因肉瘤是儿童和年轻人中最常见的骨盆恶性骨肿瘤。即使是积极的治疗,它的存活率是最差的。经典演示可能不是规则。它可以模拟临床,在影像学和组织病理学上其他非恶性实体。因此,它的怀疑不应该被忽视。我们报告了两例盆腔尤文肉瘤:第一例模仿嗜酸性肉芽肿,第二个模仿骨髓炎。在后者中,我们还报道了其自然史的非典型发现:对抗生素和抗炎治疗的初始反应.在这两种情况下,我们强调了不确定的经皮骨活检的可能性以及免疫化学和细胞遗传学对明确诊断的重要性.