Mesh : Humans Adenocarcinoma, Mucinous / diagnosis surgery pathology Sweat Gland Neoplasms / diagnosis surgery pathology Carcinoma, Skin Appendage Skin Neoplasms / diagnosis surgery pathology Sweat Glands / pathology Mucins

来  源:   DOI:10.12788/cutis.0856

Abstract:
Endocrine mucin-producing sweat gland carcinoma (EMPSGC) and primary cutaneous mucinous carcinoma (PCMC) are rare low-grade neoplasms thought to arise from apocrine glands that share many histological features and are proposed to be on a single histopathologic continuum, with EMPSGC as the in situ form that may progress to the invasive PCMC. Management involves a metastatic workup and either wide local excision (WLE) with greater than 5 mm margins or Mohs micrographic surgery (MMS) in anatomically sensitive areas. We present 2 cases of EMPSGC and 3 cases of PCMC and review their clinical and histopathologic features, differential diagnoses, and treatment.
摘要:
产生内分泌粘蛋白的汗腺癌(EMPSGC)和原发性皮肤粘液性癌(PCMC)是罕见的低度肿瘤,被认为是由具有许多组织学特征的大汗腺产生的,并且被认为是在单个组织病理学连续体上。以EMPSGC为原位形式,可能进展为侵入性PCMC。管理涉及转移性检查,以及在解剖学敏感区域进行大于5mm边缘的广泛局部切除(WLE)或Mohs显微手术(MMS)。我们介绍了2例EMPSGC和3例PCMC,并回顾了它们的临床和组织病理学特征。鉴别诊断,和治疗。
公众号