Mesh : Male Humans Middle Aged Burkholderia pseudomallei Melioidosis / diagnosis drug therapy complications Malaysia Anti-Bacterial Agents / therapeutic use Liver Abscess / drug therapy complications Hospitals, Teaching Bacteremia / complications drug therapy

来  源:   DOI:10.47665/tb.40.3.003

Abstract:
Melioidosis is endemic in Southeast Asia, including Malaysia. Liver abscess is not uncommon in melioidosis, but it is usually associated with bacteremia. We presented a case of a 55-year-old gentleman with underlying end-stage renal failure who presented with non-specific abdominal pain for three months. Initial blood investigations showed leukocytosis and increased C-reactive protein. Computed tomography (CT) of the abdomen revealed multiple hypodense lesions in the liver and spleen. The culture of the liver specimen obtained through the ultrasound-guided isolated Burkholderia pseudomallei. He was given an adjusted dose of intravenous ceftazidime due to underlying renal failure. Melioidosis serology also returned positive for IgM with titer >1:1280. His blood cultures were reported negative three times. Despite on antibiotics for five weeks, there was no significant improvement of the liver abscesses was observed. He was unfortunately infected with the SARS-CoV-2 virus during his admission and passed away due to severe COVID-19 pneumonia.
摘要:
类鼻窦炎在东南亚流行,包括马来西亚。肝脓肿在类骨病中并不少见,但通常与菌血症有关.我们介绍了一例55岁的绅士,患有潜在的终末期肾衰竭,他出现了三个月的非特异性腹痛。最初的血液检查显示白细胞增多和C反应蛋白升高。腹部计算机断层扫描(CT)显示肝脏和脾脏有多个低密度病变。通过超声引导分离的假伯克霍尔德氏菌获得的肝脏标本的培养。由于潜在的肾衰竭,他接受了调整剂量的头孢他啶静脉注射。类lioidosis血清学也返回IgM阳性,滴度>1:1280。他的血培养报告为阴性三次。尽管服用了五周的抗生素,未观察到肝脓肿的显著改善.他在入院时不幸感染了SARS-CoV-2病毒,并因严重的COVID-19肺炎去世。
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