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Abstract：
The magnitude of the diagnostic delay of symptomatic uncomplicated diverticular disease (SUDD) is unknown; we aimed to evaluate SUDD diagnostic delay and its risk factors. SUDD patients diagnosed at a tertiary referral centre were retrospectively enrolled (2010-2022). Demographic and clinical data were retrieved. Overall, patient-, and physician-dependant diagnostic delays were assessed. Univariate and multivariate analyses were fitted to identify risk factors for diagnostic delay. Overall, 70 SUDD patients (median age 65 years, IQR 52-74; F:M ratio = 1.6:1) were assessed. The median overall diagnostic delay was 7 months (IQR 2-24), patient-dependant delay was 3 months (IQR 0-15), and physician-dependant delay was 1 month (IQR 0-6). Further, 25% of patients were misdiagnosed with irritable bowel syndrome (IBS). At multivariate analysis, previous misdiagnosis was a significant risk factor for overall and physician-dependant diagnostic delay (OR 9.99, p = 0.01, and OR 6.46, p = 0.02, respectively). Also, a high educational level (> 13 years) was associated with a greater overall diagnostic delay (OR 8.74 p = 0.02), while previous abdominal surgery was significantly associated to reduced physician-dependant diagnostic delay (OR 0.19 p = 0.04). To conclude, SUDD may be diagnosed late, IBS being the most frequent misdiagnosis. Timely diagnosis is crucial to tackle the burden of SUDD on patients and healthcare.
摘要：
有症状的无并发症憩室病（SUDD）的诊断延迟程度未知；我们旨在评估SUDD诊断延迟及其危险因素。回顾性纳入在三级转诊中心诊断的SUDD患者（2010-2022年）。检索人口统计学和临床数据。总的来说,患者-,评估了与医师相关的诊断延迟.拟合单变量和多变量分析以确定诊断延迟的危险因素。总的来说,70名SUDD患者(中位年龄65岁，IQR52-74;F:M比=1.6:1)进行评估。中位总诊断延迟为7个月(IQR2-24)，患者依赖性延迟为3个月（IQR0-15），和依赖医生的延迟为1个月（IQR0-6）。Further,25%的患者被误诊为肠易激综合征(IBS)。在多变量分析中，既往误诊是总体和医师相关诊断延迟的显著危险因素(分别为OR9.99,p=0.01,和OR6.46,p=0.02).此外，高教育水平（>13年）与更大的整体诊断延迟（OR8.74p=0.02）相关，而之前的腹部手术与医师依赖性诊断延迟减少显著相关(OR0.19p=0.04).最后，SUDD可能诊断较晚，IBS是最常见的误诊。及时诊断对于解决SUDD对患者和医疗保健的负担至关重要。
