PDF(Pubmed)
Abstract：
Anopheles mosquitoes are the vectors of Plasmodium, the etiological agent of malaria. In addition, Anopheles funestus and Anopheles gambiae are the main vectors of the O\'nyong-nyong virus. However, research on the viruses carried by Anopheles is scarce; thus, the possible transmission of viruses by Anopheles is still unexplored. This systematic review was carried out to identify studies that report viruses in natural populations of Anopheles or virus infection and transmission in laboratory-reared mosquitoes. The databases reviewed were EBSCO-Host, Google Scholar, Science Direct, Scopus and PubMed. After the identification and screening of candidate articles, a total of 203 original studies were included that reported on a variety of viruses detected in Anopheles natural populations. In total, 161 viruses in 54 species from 41 countries worldwide were registered. In laboratory studies, 28 viruses in 15 Anopheles species were evaluated for mosquito viral transmission capacity or viral infection. The viruses reported in Anopheles encompassed 25 viral families and included arboviruses, probable arboviruses and Insect-Specific Viruses (ISVs). Insights after performing this review include the need for (1) a better understanding of Anopheles-viral interactions, (2) characterizing the Anopheles virome-considering the public health importance of the viruses potentially transmitted by Anopheles and the significance of finding viruses with biological control activity-and (3) performing virological surveillance in natural populations of Anopheles, especially in the current context of environmental modifications that may potentiate the expansion of the Anopheles species distribution.
摘要：
按蚊是疟原虫的媒介,疟疾的病原体。此外,按蚊和冈比亚按蚊是O\'nyong-nyong病毒的主要载体。然而,对按蚊携带的病毒的研究很少；因此，按蚊可能的病毒传播仍未被探索。进行此系统评价是为了确定报告按蚊自然种群中的病毒或实验室饲养的蚊子中的病毒感染和传播的研究。审查的数据库是EBSCO-Host，谷歌学者，科学直接，Scopus和PubMed。在对候选文章进行鉴定和筛选后，共纳入203项原始研究,报告了在按蚊自然种群中检测到的多种病毒.总的来说,来自全球41个国家的54个物种的161种病毒被注册。在实验室研究中,评估了15种按蚊物种中的28种病毒的蚊子病毒传播能力或病毒感染。按蚊报告的病毒包括25个病毒家族，包括虫媒病毒，可能的虫媒病毒和昆虫特异性病毒(ISV)。在进行此审查后的见解包括需要（1）更好地了解按蚊-病毒相互作用，（2）表征按蚊病毒-考虑到按蚊可能传播的病毒的公共卫生重要性以及发现具有生物防治活性的病毒的重要性-以及（3）在按蚊的自然种群中进行病毒学监测，特别是在当前环境变化的背景下，这可能会增强按蚊物种分布的扩展。
