PDF(Pubmed)
Abstract：
Salmonella is one of the most spread foodborne pathogens worldwide, and Salmonella infections in humans still represent a global health burden. The main source of Salmonella infections in humans is represented by contaminated animal-derived foodstuffs, with pork products being one of the most important players. Salmonella infection in swine is critical not only because it is one of the main causes of economic losses in the pork industry, but also because pigs can be infected by several Salmonella serovars, potentially contaminating the pig meat production chain and thus posing a significant threat to public health globally. As of now, in Europe and in the United States, swine-related Salmonella serovars, e.g., Salmonella Typhimurium and its monophasic variant Salmonella enterica subsp. enterica 1,4,[5],12:i:-, are also frequently associated with human salmonellosis cases. Moreover, multiple outbreaks have been reported in the last few decades which were triggered by the consumption of Salmonella-contaminated pig meat. Throughout the years, changes and evolution across the pork industry may have acted as triggers for new issues and obstacles hindering Salmonella control along the food chain. Gathered evidence reinforces the importance of coordinating control measures and harmonizing monitoring programs for the efficient control of Salmonella in swine. This is necessary in order to manage outbreaks of clinical disease in pigs and also to protect pork consumers by controlling Salmonella subclinical carriage and shedding. This review provides an update on Salmonella infection in pigs, with insights on Salmonella ecology, focusing mainly on Salmonella Choleraesuis, S. Typhimurium, and S. 1,4,[5],12:i:-, and their correlation to human salmonellosis cases. An update on surveillance methods for epidemiological purposes of Salmonella infection in pigs and humans, in a \"One Health\" approach, will also be reported.
摘要：
沙门氏菌是世界范围内传播最多的食源性致病菌之一,人类感染沙门氏菌仍然是全球健康负担。人类感染沙门氏菌的主要来源是受污染的动物源性食品，猪肉产品是最重要的参与者之一。猪沙门氏菌感染是至关重要的，不仅因为它是猪肉行业经济损失的主要原因之一，还因为猪可以被几种沙门氏菌血清型感染，可能会污染猪肉生产链，从而对全球公共卫生构成重大威胁。截至目前,在欧洲和美国，与猪相关的沙门氏菌血清型，例如，鼠伤寒沙门氏菌及其单相变异型肠沙门氏菌亚种。enterica1,4,[5],12:i:-,也经常与人类沙门氏菌病病例有关。此外，在过去的几十年中，已经报道了多起疫情，这是由食用沙门氏菌污染的猪肉引发的。多年来,整个猪肉行业的变化和演变可能是新问题的触发因素，也是阻碍食物链沙门氏菌控制的障碍。收集的证据加强了协调控制措施和协调监测计划对于有效控制猪沙门氏菌的重要性。这是必要的，以便管理猪的临床疾病爆发，并通过控制沙门氏菌亚临床携带和脱落来保护猪肉消费者。这篇综述提供了猪沙门氏菌感染的最新信息，对沙门氏菌生态学的见解，主要集中在霍乱沙门氏菌，鼠伤寒杆菌，和S.1，4，[5]，12:i:-,以及它们与人类沙门氏菌病病例的相关性。猪和人沙门氏菌感染流行病学目的监测方法的更新，在“一个健康”的方法中，也将被报道。
