关键词: Curative effect Glossopharyngeal neuralgia Microvascular decompression Percutaneous radiofrequency thermocoagulation Prognosis

Mesh : Humans Retrospective Studies Microvascular Decompression Surgery Treatment Outcome Glossopharyngeal Nerve Diseases / surgery etiology Electrocoagulation Pain / etiology Trigeminal Neuralgia / surgery

来  源:   DOI:10.1186/s12883-023-03415-z   PDF(Pubmed)

Abstract:
OBJECTIVE: This study aimed to investigate the differences in the effectiveness of percutaneous radiofrequency thermocoagulation (PRT) and microvascular decompression (MVD) in treating glossopharyngeal neuralgia (GPN).
METHODS: Medical records of patients were reviewed to investigate their baseline characteristics and immediate postoperative prognosis. Long-term outcomes of these patients were obtained through telephone interviews. Visual analog scale (VAS) and Pittsburgh sleep quality index (PSQI) scores at 1 day and 1, 4, 12, 24, and 48 weeks after surgery were compared between the MVD and PRT groups, in addition to complete pain relief rate, effective rate, adverse reactions, length of hospital stay, and economic indicators.
RESULTS: The VAS and PSQI scores of the two groups at 1 day and 1, 4, 12, 24, and 48 weeks after surgery were significantly lower (P < 0.05) than those before surgery. At 48 weeks, the complete remission rate was significantly higher (P < 0.05) in the MVD group than in PRT group. No significant difference in adverse reactions was observed between the two groups. The length of hospital stay, operative time, and cost were significantly higher (P < 0.05) in the MVD group than in the PRT group.
CONCLUSIONS: Both PRT and MVD can significantly reduce patients\' degree of pain and improve their sleep quality. In the medium term, MVD is better than PRT in terms of the complete curative effect. In young patients with GPN, MVD is more often recommended than PRT; however, MVD is costlier than PRT.
摘要:
目的:本研究旨在探讨经皮射频热凝(PRT)和微血管减压术(MVD)治疗舌咽神经痛(GPN)的疗效差异。
方法:回顾了患者的病历,以调查他们的基线特征和术后近期预后。这些患者的长期结果是通过电话采访获得的。比较MVD组和PRT组术后1天和术后1、4、12、24、48周的视觉模拟量表(VAS)和匹兹堡睡眠质量指数(PSQI)评分,除了疼痛完全缓解率,有效率,不良反应,住院时间,和经济指标。
结果:两组术后1天、1、4、12、24、48周的VAS和PSQI评分较术前明显降低(P<0.05)。48周时,MVD组完全缓解率明显高于PRT组(P<0.05)。两组不良反应比较差异无统计学意义。住院时间长短,手术时间,MVD组及费用均显著高于PRT组(P<0.05)。
结论:PRT和MVD均能显著减轻患者疼痛程度,改善患者睡眠质量。从中期来看,MVD在完整疗效方面优于PRT。在年轻的GPN患者中,MVD比PRT更常被推荐;然而,MVD比PRT昂贵。
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