METHODS: We performed a literature search of the electronic databases PubMed, Web of Science, Cochrane Library, Embase, CNKI, CBM, WanFang Data, and VIP from their inception to 16 May 2023. The primary outcome was the 6-min walk test (6MWT), while the secondary outcomes were anxiety levels and quality of life (QoL). Two independent reviewers performed the data extraction using a predefined protocol and assessed the risk of bias using the Cochrane risk of bias (ROB) tool for randomized controlled trials, with differences agreed by consensus. Meta-analysis was performed using RevMan 5.4 and Stata 15 software to analyze the extracted data.
RESULTS: This meta-analysis included a total of 11 studies involving 897 patients. The results indicated that compared to the usual care group, lung cancer patients in the mind-body exercise group could increase the 6-min walk distance (5 studies, 346 participants, WMD: 18.83, 95% CI (7.55, 30.10) P = 0.001), reduce anxiety levels (4 studies, 362 participants, SMD: - 1.51, 95% CI (- 1.74, - 1.27), P < 0.05), and enhance the overall quality of life (6 studies, 594 participants, SMD: 0.71, 95% CI (0.10, 1.31), P = 0.02). The overall certainty of the evidence for all outcomes was low; seven studies were judged to be at low risk of bias, and four studies were judged to be at moderate risk of bias.
CONCLUSIONS: Mind-body exercise could improve exercise capacity in lung cancer survivors, reduce anxiety, and positively affect overall quality of life.
UNASSIGNED: CRD42023426800.
方法:我们对电子数据库PubMed进行了文献检索,WebofScience,科克伦图书馆,Embase,CNKI,CBM,万方数据,和VIP从成立到2023年5月16日。主要结果是6分钟步行测试(6MWT),而次要结局是焦虑水平和生活质量(QoL)。两名独立评审员使用预定义的方案进行数据提取,并使用Cochrane偏倚风险(ROB)工具对随机对照试验进行偏倚风险评估。以协商一致方式达成的分歧。采用RevMan5.4和Stata15软件对提取的数据进行Meta分析。
结果:本荟萃分析共纳入11项研究,涉及897名患者。结果表明,与常规护理组相比,心身运动组的肺癌患者可以增加6分钟步行距离(5项研究,346名参与者,大规模毁灭性武器:18.83,95%CI(7.55,30.10)P=0.001),降低焦虑水平(4项研究,362名参与者,SMD:-1.51,95%CI(-1.74,-1.27),P<0.05),并提高整体生活质量(6项研究,594名参与者,SMD:0.71,95%CI(0.10,1.31),P=0.02)。所有结果的证据的总体确定性较低;七项研究被认为是低偏倚风险。4项研究被判断为中度偏倚风险.
结论:身心锻炼可以提高肺癌幸存者的运动能力,减少焦虑,并积极影响整体生活质量。
■CRD42023426800。