Abstract：
Ticks are the main vectors for the transmission of bacterial, protist and viral pathogens in Europe affecting wildlife and domestic animals. However, some of them are zoonotic and can cause serious, sometimes fatal, problems in human health. A systematic review in PubMed/MEDLINE database was conducted to determine the spatial distribution and host and tick species ranges of a selection of tick-borne bacteria (Anaplasma spp., Borrelia spp., Coxiella spp., and Rickettsia spp.), protists (Babesia spp. and Theileria spp.), and viruses (Orthonairovirus, and flaviviruses tick-borne encephalitis virus and louping ill virus) on the European continent in a five-year period (November 2017 - November 2022). Only studies using PCR methods were selected, retrieving a total of 429 articles. Overall, up to 85 species of the selected tick-borne pathogens were reported from 36 European countries, and Anaplasma spp. was described in 37% (159/429) of the articles, followed by Babesia spp. (34%, 148/429), Borrelia spp. (34%, 147/429), Rickettsia spp. (33%, 142/429), Theileria spp. (11%, 47/429), tick-borne flaviviruses (9%, 37/429), Orthonairovirus (7%, 28/429) and Coxiella spp. (5%, 20/429). Host and tick ranges included 97 and 50 species, respectively. The highest tick-borne pathogen diversity was detected in domestic animals, and 12 species were shared between humans, wildlife, and domestic hosts, highlighting the following zoonotic species: Anaplasma phagocytophilum, Babesia divergens, Babesia microti, Borrelia afzelii, Borrelia burgdorferi s.s., Borrelia garinii, Borrelia miyamotoi, Crimean-Congo hemorrhagic fever virus, Coxiella burnetii, Rickettsia monacensis and tick-borne encephalitis virus. These results contribute to the implementation of effective interventions for the surveillance and control of tick-borne diseases.
摘要：
蜱是细菌传播的主要载体，欧洲的原生生物和病毒病原体影响野生动物和家畜。然而,其中一些是人畜共患的，可能会导致严重的，有时是致命的,人类健康问题。在PubMed/MEDLINE数据库中进行了系统评价，以确定选定的tick传播细菌的空间分布以及宿主和tick种范围（Anaplasmaspp。,疏螺旋体属。,柯希拉属。,和立克次体。),原生生物(巴贝西亚属。和Theileriaspp.),和病毒(正负病毒，和黄病毒蜱传脑炎病毒和肺平病病毒）在欧洲大陆的五年期间（2017年11月至2022年11月）。仅选择使用PCR方法的研究，共检索到429篇文章。总的来说,从36个欧洲国家报告了多达85种选定的蜱传病原体，和无性体。在37%(159/429)的文章中进行了描述，其次是Babesiaspp。（34%，148/429），疏螺旋体属。（34%，147/429），立克次体属。（33%，142/429),Theileriaspp.（11%，47/429），蜱传黄病毒(9%，37/429），正负病毒(7%，28/429）和柯西氏菌属。(5%,20/429）。寄主和蜱范围包括97和50种，分别。在家畜中检测到最高的tick传播病原体多样性，人类共有12个物种，野生动物,和国内主机，突出以下人畜共患物种：吞噬细胞无性体，分歧性巴贝虫,米蒂巴贝虫,afzelii伯氏螺旋体,伯氏疏螺旋体s.s.，Galinii疏螺旋体,miyamotoiBorreliamiyamotoi,克里米亚-刚果出血热病毒,伯内蒂柯西拉,立克次体和蜱传脑炎病毒。这些结果有助于实施有效的干预措施来监测和控制蜱传疾病。
