关键词: Choroidal thickness Microgravity Ocular rigidity Space flight Valsalva

来  源:   DOI:10.1016/j.ajoc.2023.101940   PDF(Pubmed)

Abstract:
UNASSIGNED: To evaluate ocular rigidity and choroidal thickness changes in response to microgravity and the Valsalva maneuver in a private astronaut.
UNASSIGNED: Ophthalmological examination and Optical Coherence Tomography were performed before, during, and after space flight. Choroidal thickness was measured at all time points at rest and during the Valsalva maneuver. Ocular rigidity was obtained before and after flight using a non-invasive method enhanced with deep learning-based choroid segmentation.
UNASSIGNED: Ocular rigidity decreased after space flight compared to baseline. There was an increase in average choroidal thickness during the Valsalva maneuver compared to the resting condition before, during, and after space flight, and such increase was greater when the Valsalva maneuver was performed during space flight.
UNASSIGNED: The data indicates biomechanical changes to ocular tissues because of space flight and greater choroidal thickness increase. The findings could lead to a better understanding of space flight-associated neuro-ocular syndrome and may have repercussions for short duration missions in a nascent industry.
摘要:
评估对微重力和私人宇航员中的Valsalva机动的响应的眼刚度和脉络膜厚度变化。
之前进行了眼科检查和光学相干断层扫描,during,在太空飞行之后。在休息和Valsalva动作期间的所有时间点测量脉络膜厚度。使用基于深度学习的脉络膜分割增强的非侵入性方法,在飞行之前和之后获得眼球刚度。
太空飞行后,与基线相比,眼刚度下降。与之前的静息状态相比,在Valsalva动作期间平均脉络膜厚度增加,during,在太空飞行之后,当在太空飞行中进行Valsalva动作时,这种增加更大。
数据表明,由于太空飞行和脉络膜厚度增加,眼组织的生物力学变化。这些发现可能会使人们更好地了解与太空飞行相关的神经眼综合症,并可能对新兴行业中的短期任务产生影响。
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