{Reference Type}: Journal Article
{Title}: Ocular rigidity and choroidal thickness changes in response to microgravity: A case study.
{Author}: Masís Solano M;Bélanger Nzakimuena C;Dumas R;Lesk MR;Costantino S;
{Journal}: Am J Ophthalmol Case Rep
{Volume}: 32
{Issue}: 0
{Year}: 2023 Dec
暂无{DOI}: 10.1016/j.ajoc.2023.101940
{Abstract}: <B>UNASSIGNED: </B>To evaluate ocular rigidity and choroidal thickness changes in response to microgravity and the Valsalva maneuver in a private astronaut.<BR><B>UNASSIGNED: </B>Ophthalmological examination and Optical Coherence Tomography were performed before, during, and after space flight. Choroidal thickness was measured at all time points at rest and during the Valsalva maneuver. Ocular rigidity was obtained before and after flight using a non-invasive method enhanced with deep learning-based choroid segmentation.<BR><B>UNASSIGNED: </B>Ocular rigidity decreased after space flight compared to baseline. There was an increase in average choroidal thickness during the Valsalva maneuver compared to the resting condition before, during, and after space flight, and such increase was greater when the Valsalva maneuver was performed during space flight.<BR><B>UNASSIGNED: </B>The data indicates biomechanical changes to ocular tissues because of space flight and greater choroidal thickness increase. The findings could lead to a better understanding of space flight-associated neuro-ocular syndrome and may have repercussions for short duration missions in a nascent industry.