关键词: cerebellopontine angle epidermoid cyst lesionectomy temporal lobe epilepsy tumor-related epilepsy

来  源:   DOI:10.7759/cureus.45360   PDF(Pubmed)

Abstract:
Epidermoid cysts represent roughly 1% of all intracranial tumors. They are frequently located in the cerebellopontine angle but rarely extend to the supratentorial brain. Epilepsy is an extremely uncommon manifestation of this neoplasm. We suggest the surgical management of a 35-year-old male who presented with a six-month history of intractable temporal lobe epilepsy. His seizures were characterized by a focal onset in the form of déjà vu experiences, followed by a secondarily generalized tonic-clonic seizure. Imaging revealed a heterogeneous cystic mass in the right cerebellopontine angle, extending supratentorially causing a mass effect on the mesial temporal region. Gross total resection was achieved through a combined subtemporal-retrosigmoid approach. Histopathology revealed an epidermoid cyst. The patient was entirely seizure-free at the three-month follow-up. Epidermoid cysts may present with epileptic seizures. Seizure freedom can be achieved with surgical management in most cases. The patient\'s symptoms, imaging findings, and epileptogenic focus must be considered to select the appropriate surgical strategy.
摘要:
表皮样囊肿约占所有颅内肿瘤的1%。它们通常位于小脑桥脑角,但很少延伸到幕上脑。癫痫是这种肿瘤极其罕见的表现。我们建议对一名35岁的男性进行手术治疗,该男性有六个月的难治性颞叶癫痫病史。他的癫痫发作的特点是以似曾相识的经验形式出现局灶性发作,其次是全身性强直-阵挛性癫痫发作。影像学显示右侧小脑桥脑角有一个不均匀的囊性肿块,向上延伸,对内侧颞区产生质量影响。通过合并颞下乙状窦后入路实现了大体全切除。组织病理学发现表皮样囊肿。在三个月的随访中,患者完全没有癫痫发作。表皮样囊肿可伴有癫痫发作。在大多数情况下,手术治疗可以实现癫痫发作的自由度。病人的症状,影像学发现,选择合适的手术策略必须考虑癫痫灶。
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