关键词: Laryngeal squamous-cell carcinoma anterior commissure glottis type laryngeal stenosis partial laryngectomy recurrence

Mesh : Humans Laryngectomy Glottis / surgery pathology Laryngostenosis / surgery Retrospective Studies Carcinoma, Squamous Cell Laryngeal Neoplasms

来  源:   DOI:10.1080/00016489.2023.2265436

Abstract:
UNASSIGNED: The current treatment options for T1b glottic carcinoma often lead to poor treatment outcomes or voice quality.
UNASSIGNED: This study evaluates the therapeutic efficacy of horizontal middle partial laryngectomy with cricothyroidopexy (HMPL-CTP) for stage T1b glottic carcinoma.
UNASSIGNED: A retrospective analysis was conducted on 73 patients with T1b glottic carcinoma. The patients were categorized into three groups: Group A (n = 22) underwent transoral laser microsurgery (TLMS), Group B (n = 21) received frontolateral vertical partial laryngectomy (FVPL), and Group C (n = 30) underwent HMPL-CTP. The study analyzed the 5-year overall survival rate (OS), recurrence rate, phonatory status, and incidence of laryngeal stenosis.
UNASSIGNED: Voice quality scores varied significantly in the three groups, while the 5-year OS were similar. The local recurrence rate is higher in Group A than in the other two groups. The laryngeal stenosis rate in Group B is higher than in Groups A and C. Adhesions in the anterior commissure were observed in 18 cases in Group A and nine cases in Group C.
UNASSIGNED: HMPL-CTP demonstrates efficacy as a treatment for stage T1b glottic carcinoma, offering favorable preservation of laryngeal function and minimal complications.
摘要:
目前T1b声门型喉癌的治疗方案往往导致不良的治疗结果或语音质量。
本研究评估了水平中喉部分切除术联合环甲切除术(HMPL-CTP)治疗T1b期声门型喉癌的疗效。
对73例T1b声门型喉癌患者进行回顾性分析。将患者分为三组:A组(n=22)接受经口激光显微手术(TLMS),B组(n=21)接受额外侧垂直喉部分切除术(FVPL),C组(n=30)行HMPL-CTP。该研究分析了5年总生存率(OS),复发率,语音状态,和喉部狭窄的发生率。
三组的语音质量得分差异很大,而5年OS相似。A组的局部复发率高于其他两组。B组喉狭窄率高于A组和C组。A组18例,C组9例,观察到前连合粘连。
HMPL-CTP显示出治疗T1b期声门癌的疗效,提供良好的喉功能和最小的并发症。
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