PDF(Pubmed)
Abstract：
BACKGROUND: Not much is known about the significance of nutritional status and support in transplant surgery, least of all in simultaneous pancreatic and kidney transplantation. Malnutrition in the context of simultaneous pancreatic-kidney transplantation seems to be complex and a still poorly investigated problem. Since SPKTX is highly qualified and also has a small volume procedure, it is difficult to obtain data from large cohorts of patients. The aim of this article is to gather existing evidence and information about the subject, as well as to elicit some questions and goals for the future.
METHODS: We searched through the Pub-Med database using the keywords \"pancreas and kidney transplantation\" combined with \"nutritional risk\", \"nutritional status\", \"malnutrition\", \"nutritional intervention\", and \"frailty\", finding a total of 4103 matching results. We then narrowed it down to articles written in English with the full text available. We also researched through the references of articles most accurately matching our researched terms.
RESULTS: There are numerous tools that have been investigated for the screening of malnutrition, such as the NRI index, PNI index, NLR, SGA scale, and NRS-2002 scale, each of which proved to be of some use in predicting patient outcomes in different surgical settings. Since all of them differed in components and assessed parameters and, in the absence of more sensitive or infallible indicators, the most reasonable approach seems to evaluate them jointly.
CONCLUSIONS: It is important to underline the necessity of nutritional screening and the subsequent introduction of adequate therapy while awaiting transplantation in an attempt to improve results. Considering the complexity of surgical procedures and the severity of underlying diseases with their intense metabolic components, the patient\'s nutritional status seems to significantly influence results. Consequently, nutritional risk assessments should be a part of the routine care of patients qualified for transplantation.
METHODS: We searched through the Pub-Med database using the keywords \"pancreas and kidney transplantation\" combined with \"nutritional risk\", \"nutritional status\", \"malnutrition\", \"nutritional intervention\", and \"frailty\", finding a total of 4103 matching results. We then narrowed it down to articles written in English with the full text available. We also researched through the references of articles most accurately matching our researched terms.
RESULTS: There are numerous tools that have been investigated for the screening of malnutrition, such as the NRI index, PNI index, NLR, SGA scale, and NRS-2002 scale, each of which proved to be of some use in predicting patient outcomes in different surgical settings. Since all of them differed in components and assessed parameters and, in the absence of more sensitive or infallible indicators, the most reasonable approach seems to evaluate them jointly.
CONCLUSIONS: It is important to underline the necessity of nutritional screening and the subsequent introduction of adequate therapy while awaiting transplantation in an attempt to improve results. Considering the complexity of surgical procedures and the severity of underlying diseases with their intense metabolic components, the patient\'s nutritional status seems to significantly influence results. Consequently, nutritional risk assessments should be a part of the routine care of patients qualified for transplantation.
摘要：
背景：关于营养状况和支持在移植手术中的重要性知之甚少，尤其是同时进行胰腺和肾脏移植。在同时进行胰肾移植的情况下，营养不良似乎很复杂，并且仍然是一个研究不足的问题。由于SPKTX是高度合格的，也有一个小体积的过程，很难从大型患者队列中获取数据.本文的目的是收集有关该主题的现有证据和信息，以及引出一些未来的问题和目标。
方法：我们搜索了Pub-Med数据库，使用关键词“胰腺和肾脏移植”和“营养风险”，“营养状况”，“营养不良”，“营养干预”，和“脆弱”，查找共4103个匹配结果。然后，我们将其范围缩小到用英语写的文章，全文可用。我们还通过最准确地匹配我们研究的术语的文章的参考文献进行了研究。
结果：已经研究了许多用于筛查营养不良的工具，例如NRI指数，PNI指数,NLR,SGA量表,和NRS-2002量表，每种方法都被证明在预测不同手术环境下的患者结局方面有一定的用处.由于它们在成分和评估参数上都不同，在没有更敏感或可靠的指标的情况下，最合理的方法似乎是共同评估它们。
结论：重要的是强调营养筛查的必要性，以及随后在等待移植以改善结果的同时引入适当的治疗方法。考虑到外科手术的复杂性和潜在疾病的严重程度及其强烈的代谢成分，患者的营养状况似乎对结果有显著影响。因此,营养风险评估应该是有资格接受移植的患者的常规护理的一部分.
方法：我们搜索了Pub-Med数据库，使用关键词“胰腺和肾脏移植”和“营养风险”，“营养状况”，“营养不良”，“营养干预”，和“脆弱”，查找共4103个匹配结果。然后，我们将其范围缩小到用英语写的文章，全文可用。我们还通过最准确地匹配我们研究的术语的文章的参考文献进行了研究。
结果：已经研究了许多用于筛查营养不良的工具，例如NRI指数，PNI指数,NLR,SGA量表,和NRS-2002量表，每种方法都被证明在预测不同手术环境下的患者结局方面有一定的用处.由于它们在成分和评估参数上都不同，在没有更敏感或可靠的指标的情况下，最合理的方法似乎是共同评估它们。
结论：重要的是强调营养筛查的必要性，以及随后在等待移植以改善结果的同时引入适当的治疗方法。考虑到外科手术的复杂性和潜在疾病的严重程度及其强烈的代谢成分，患者的营养状况似乎对结果有显著影响。因此,营养风险评估应该是有资格接受移植的患者的常规护理的一部分.
