Abstract：
Halogenated organic compounds (HOCs), widely present in various environments, are generally formed by natural processes (e.g., photochemical halogenation) and anthropogenic activities (e.g., water disinfection and anthropogenic discharge of HOCs), posing health and environmental risks. Therefore, in-depth knowledge of the molecular composition, transformation, and fate of HOCs is crucial to regulate and reduce their formation. Because of the extremely complex nature of HOCs and their precursors, the molecular composition of HOCs remains largely unknown. The Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) offers the most powerful resolution and mass accuracy for the simultaneous molecular-level characterization of HOCs and their precursors. However, there is still a paucity of reviews regarding the comprehensive characterization of HOCs by FT-ICR MS. Based on the FT-ICR MS, the formation mechanism, sample pretreatment, and analysis methods were summarized for two typical HOCs classes, namely halogenated disinfection byproducts and per- and polyfluoroalkyl substances in this review. Moreover, we have highlighted data analysis methods and some typical applications of HOCs using FT-ICR MS and proposed suggestions for current issues. This review will deepen our understanding of the chemical characterization of HOCs and their formation mechanisms and transformation at the molecular level in aquatic systems, facilitating the application of the state-of-the-art FT-ICR MS in environmental and geochemical research.
摘要：
卤化有机化合物（HOC），广泛存在于各种环境中，通常是由自然过程形成的(例如，光化学卤化)和人为活动(例如，水消毒和HOC的人为排放)，带来健康和环境风险。因此,深入了解分子组成，改造,HOC的命运对调节和减少其形成至关重要。由于HOCs及其前体的极其复杂的性质，HOCs的分子组成在很大程度上仍然未知。傅里叶变换离子回旋共振质谱（FT-ICRMS）为HOC及其前体的同时分子级表征提供了最强大的分辨率和质量精度。然而,关于FT-ICRMS对HOC的全面表征的评论仍然很少。根据FT-ICRMS，形成机制,样品预处理,并总结了两种典型HOC类别的分析方法，本文综述了卤化消毒副产物和全氟烷基和多氟烷基物质。此外，我们重点介绍了使用FT-ICRMS的数据分析方法和HOC的一些典型应用，并对当前问题提出了建议。这篇综述将加深我们对水系统中HOCs的化学表征及其在分子水平上的形成机制和转化的理解，促进最先进的FT-ICRMS在环境和地球化学研究中的应用。
