METHODS: Thirty-two young non-obese rats were randomly divided into four equal groups. Both the standard diet and the high-protein ketogenic diet were given ad libitum and intermittently to the rats for 6 wk. The body weight and fat mass of the rats were measured at the end of the experiment. The fasting glucose, leptin, insulin, high- and low-density lipoprotein, and triacylglycerols were measured with the blood samples.
RESULTS: The lowest body weight was observed in the intermittent and high-protein ketogenic diet group, followed by the free high-protein ketogenic diet and standard intermittent diet group, respectively. Also, the lowest body fat mass was observed in the intermittent and high-protein ketogenic diet group, followed by the standard intermittent diet group. Although there was no change in leptin, insulin, high- and low-density lipoprotein, and triacylglycerol levels in any group, the lowest blood glucose rate was observed in the intermittent and high-protein ketogenic diet group.
CONCLUSIONS: The results of the present study revealed that an intermittent high-protein ketogenic diet is more effective than others in weight loss without disrupting biochemical health parameters, and the applied diets do not prevent growth and development.
方法:将32只幼年非肥胖大鼠随机分为4组。标准饮食和高蛋白生酮饮食均随意给予大鼠,并间歇性给予大鼠6周。在实验结束时测量大鼠的体重和脂肪量。空腹血糖,瘦素,胰岛素,高密度和低密度脂蛋白,和三酰甘油用血样测定。
结果:在间歇性和高蛋白生酮饮食组中观察到最低体重,其次是免费高蛋白生酮饮食和标准间歇饮食组,分别。此外,在间歇性和高蛋白生酮饮食组中观察到最低的体脂质量,其次是标准间歇饮食组。虽然瘦素没有变化,胰岛素,高密度和低密度脂蛋白,和三酰甘油在任何组中的水平,间歇性和高蛋白生酮饮食组的血糖率最低.
结论:本研究的结果表明,间歇性高蛋白生酮饮食在减肥方面比其他饮食更有效,而不会破坏生化健康参数,和应用的饮食不阻止生长和发育。