关键词: Alginate Chitosan Diabetic wound Marine polysaccharide Wound healing

Mesh : Wound Healing Polysaccharides / pharmacology therapeutic use Hydrogels Bandages

来  源:   DOI:10.1016/j.ijbiomac.2023.127331

Abstract:
Polysaccharides originating from marine sources have been studied as potential material for use in wound dressings because of their desirable characteristics of biocompatibility, biodegradability, and low toxicity. Marine-derived polysaccharides used as wound dressing, provide several benefits such as promoting wound healing by providing a moist environment that facilitates cell migration and proliferation. They can also act as a barrier against external contaminants and provide a protective layer to prevent further damage to the wound. Research studies have shown that marine-derived polysaccharides can be used to develop different types of wound dressings such as hydrogels, films, and fibres. These dressings can be personalised to meet specific requirements based on the type and severity of the wound. For instance, hydrogels can be used for deep wounds to provide a moist environment, while films can be used for superficial wounds to provide a protective barrier. Additionally, these polysaccharides can be modified to improve their properties, such as enhancing their mechanical strength or increasing their ability to release bioactive molecules that can promote wound healing. Overall, marine-derived polysaccharides show great promise for developing effective and safe wound dressings for various wound types.
摘要:
由于其理想的生物相容性特性,来自海洋来源的多糖已被研究作为用于伤口敷料的潜在材料。生物降解性,和低毒性。用作伤口敷料的海洋衍生多糖,通过提供促进细胞迁移和增殖的潮湿环境,例如促进伤口愈合。它们还可以充当抵抗外部污染物的屏障并提供保护层以防止对伤口的进一步损害。研究表明,海洋衍生的多糖可用于开发不同类型的伤口敷料,如水凝胶,电影,和纤维。这些敷料可以是个性化的,以满足基于伤口类型和严重程度的具体要求。例如,水凝胶可用于深层伤口,以提供潮湿的环境,而薄膜可用于表面伤口以提供保护性屏障。此外,这些多糖可以被修饰以改善其性质,例如增强其机械强度或增加其释放可促进伤口愈合的生物活性分子的能力。总的来说,海洋衍生的多糖在开发各种伤口类型的有效和安全的伤口敷料方面显示出巨大的希望。
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