Abstract：
Objectives: Two headphone systems using different sound systems were compared to investigate the effects of a sound intervention on cardiovascular parameters, indicators of stress, and subjective feelings. Methods: One hundred volunteers who work in the health care sector reporting elevated workplace-related stress were enrolled and randomized to a 12-min sound intervention (classical music) with either conventional headphones (\"MEZE 99 Classic\") or with the same-but internally modified-headphone (called \"Lautsaenger\"). Cardiovascular parameters were measured with the VascAssist2.0, both before and after sound interventions. In addition, participants were asked to complete questionnaires on burnout risk and emotions/stress. Results: The study population consisted mainly of female participants (n = 83), with the majority being students (42%). Median age was 32.5 years (range 21-71). In terms of cardiovascular parameters, a significant reduction in aortic pulse wave velocity, as measure of arterial stiffness, and heart rate was observed within both treatment arms. Both systolic blood pressure and arterial flow resistance were reduced by sound intervention, while these effects were only documented with Lautsaenger. Treatment groups were comparable in terms of subjective feedback by participants: a significant increase in emotional wellbeing was achieved with both headphone systems. Conclusions: A single short-term sound intervention seems to be able to achieve objective cardiovascular improvements in healthy volunteers reporting subjective symptoms of workplace-related stress, using two different headphone systems. Moreover, significant emotional improvement was reported within both arms. Trial Registration: ISRCTN registry 70947363, date of registration August 13, 2021.
摘要：
目标：比较了使用不同声音系统的两种耳机系统，以研究声音干预对心血管参数的影响。压力指标，和主观感受。方法：招募了100名在医疗保健部门工作的志愿者，他们报告了与工作场所相关的压力升高，并随机使用常规耳机（“MEZE99Classic”）或使用相同但内部修改的耳机（称为“Lautsaenger”）进行12分钟的声音干预（古典音乐）。在合理干预之前和之后，使用VascAssist2.0测量心血管参数。此外,参与者被要求完成关于倦怠风险和情绪/压力的问卷.结果：研究人群主要为女性参与者（n=83），大多数是学生（42%）。中位年龄为32.5岁（范围21-71）。就心血管参数而言，主动脉脉搏波速度显著降低,作为动脉僵硬度的量度,在两个治疗组中观察到心率。通过合理干预，收缩压和动脉流动阻力均降低，而这些影响只有Lautsaenger记录。治疗组在参与者的主观反馈方面具有可比性：两种耳机系统均实现了情绪健康的显着增加。结论：在报告工作场所相关压力的主观症状的健康志愿者中，单一的短期合理干预似乎能够实现客观的心血管改善。使用两种不同的耳机系统。此外，据报道,两组患者的情绪均有显著改善.试用注册：ISRCTN注册70947363，注册日期2021年8月13日。
