UNASSIGNED: Evidence for a novel Malacoplasma sp. was discovered by in vivo Illumina metatranscriptomics sequencing of the T. gallinae-infected pigeon mouth. We leveraged published 16S rDNA profiling data from digestive tract of 12 healthy and 24 T. gallinae-infected pigeons to investigate association between the novel Malacoplasma sp. and T. gallinae. We utilised Illumina metagenomics sequencing targeted to pigeon oral and crop samples infected with the novel Malacoplasma sp. to generate its full-length genome sequence. Sequence similarity network analysis was used to compare annotated proteins from the novel Malacoplasma sp. with a range of other related species.
UNASSIGNED: Here we present evidence for a novel Malacoplasma species, related to \"Ca. M. girerdii,\" that is strongly associated with T. gallinae in the upper digestive tract of domestic pigeons. Analysis of the genome sequence revealed gene features apparently specific to a Trichomonas-symbiotic Malacoplasma lineage.
UNASSIGNED: These data support a model of long-term association between Trichomonas and Malacoplasma spp. that has been conserved across diversification of the Trichomonas lineage and the host species barrier from birds to human.
■新型疟原虫的证据。是通过体内Illumina转移转录组学测序发现的。我们利用已发表的来自12只健康和24只感染了鸡的鸽子的消化道的16SrDNA分析数据来研究新型的疟原虫之间的关联。还有T.gallinae.我们利用Illumina宏基因组学测序技术针对感染了新型疟原虫的鸽子口腔和作物样品。生成其全长基因组序列。序列相似性网络分析用于比较来自新型疟原虫的注释蛋白质。与一系列其他相关物种。
■在这里,我们提供了一种新的疟原虫物种的证据,与“Ca”有关。M.girerdii,这与家鸽上消化道中的鸡毛虫密切相关。对基因组序列的分析揭示了毛滴虫共生的疟原虫谱系显然具有特异性的基因特征。
■这些数据支持毛滴虫和疟原虫之间的长期关联模型。在毛滴虫谱系的多样化和从鸟类到人类的宿主物种屏障中得到了保护。