Multiple intra-abdominal fungal granulomas caused by Scedosporium apiospermum effectively treated with voriconazole in a Golden Retriever.

金毛中的伏立康唑有效治疗了由 Scedo 孢子菌引起的多发性腹内真菌性肉芽肿。

• 发表时间: 2023 Dec
• 来源期刊: Med Mycol Case Rep
• DOI: 10.1016/j.mmcr.2023.100611
• PMID: 37808222
• 文章类型: Case Reports
• 作者列表: Yoshimura A,Fukushima R,Michishita M,Omura M,Makimura K,Azakami D

关键词: Dog; Fungal granuloma; Fungal infection; Scedosporium apiospermum; Voriconazole

Abstract

Scedosporium apiospermum is a saprophytic filamentous fungus that is pathogenic to dogs. This report describes a case of S. apiospermum infection that caused multiple large peritoneal fungal granulomas in a dog with a history of jejunojejunostomy. The lesions were firmly attached to multiple organs and could not be surgically removed. In such cases, no precedent for the response to the treatment of this disease exists, and all affected dogs have died. This is the first report of an effective medical treatment for multiple intra-abdominal fungal granulomas using voriconazole.

摘要

Scedosporiumapiospermum是一种腐生丝状真菌，对狗有致病性。本报告描述了一例Papiospermum感染，该感染在有空肠空肠吻合术史的狗中引起多发性大腹膜真菌性肉芽肿。病变牢固地附着在多个器官上，无法通过手术切除。在这种情况下,对这种疾病的治疗没有先例，所有受影响的狗都死了。这是使用伏立康唑有效治疗多发性腹内真菌性肉芽肿的第一份报告。