Abstract:
Secretory carcinoma (SC) was originally described as mammary analogue secretory carcinoma (MASC). We present here a case of 33 years old male who came to ENT outpatient department with a complaint of swelling over the left side of his neck for 8 months. On Fine-needle aspiration cytology, an impression of cytomorphological features suggestive of acinic cell carcinoma (Milan category V) was given. Left functional endoscopic sinus surgery was done. On histopathology, a final impression of Secretory carcinoma, the left submandibular gland was given with pathological stage classification as pT2N0Mx. SC of the salivary gland is a rare entity that may pose diagnostic challenges. Awareness of its cytologic features is paramount to achieve an accurate diagnosis. Morphologic interpretation must be supported by an immunohistochemical profile and molecular studies to confirm a diagnosis of SC.
摘要:
分泌性癌(SC)最初被描述为乳腺类似物分泌性癌(MASC)。我们在这里介绍一例33岁的男性,他来到耳鼻喉科门诊部,抱怨颈部左侧肿胀8个月。细针穿刺细胞学检查,给出了提示腺泡细胞癌(米兰V类)的细胞形态学特征的印象。左功能性内镜鼻窦手术。在组织病理学上,分泌性癌的最后印象,给予左颌下腺,病理分期为pT2N0Mx。唾液腺SC是一种罕见的实体,可能会带来诊断挑战。了解其细胞学特征对于实现准确诊断至关重要。形态学解释必须得到免疫组织化学谱和分子研究的支持,以确认SC的诊断。