Abstract：
Sclerosing odontogenic carcinoma (SOC) is a very rare malignant odontogenic tumor characterized by sclerotic stroma and single-file cord-like tumor cell structures. A 38-year-old man presented with extraoral swelling and right mental region paralysis. Panoramic radiography revealed an ill-defined radiolucent lesion extending from the right mandibular ramus to the right lower canine. Magnetic resonance imaging showed tumor invasion into the right inferior alveolar nerve and masseter muscle. Hemimandibulectomy, bilateral neck dissection, and mandibular reconstruction were performed using a rectus abdominis musculocutaneous flap and a titanium plate. Histopathology and immunohistochemistry confirmed SOC diagnosis. No recurrence occurred in the 1-year follow-up. In this paper, a case of SOC with a high Ki-67 labeling index was reported. Since SOC is prone to nerve invasion, treatment is resection with an appropriate surgical margin.
摘要：
硬化性牙源性癌（SOC）是一种非常罕见的恶性牙源性肿瘤，其特征是硬化性间质和单排索状肿瘤细胞结构。一名38岁的男子出现口外肿胀和右精神区域瘫痪。全景X线检查显示，从右下颌支延伸到右下犬科动物的放射状病变不明确。磁共振成像显示肿瘤侵入右侧下牙槽神经和咬肌。半脑切除术,双侧颈淋巴结清扫术,使用腹直肌肌皮瓣和钛板进行下颌骨重建。组织病理学和免疫组织化学证实了SOC诊断。随访1年无复发。在本文中,报告1例Ki-67标记指数较高的SOC.由于SOC容易侵犯神经，治疗是切除与适当的手术切缘。
