Abstract：
Iron uptake, transport, and storage require the involvement of several proteins, including ferroportin (fpn), the sole known iron efflux transporter. Due to its critical function fpn has been studied, particularly in humans. Here, we characterized the ferroportin gene in common carp (Cyprinus carpio L.) and performed RNA-seq analysis to evaluate its constitutive transcription levels across different tissues. Our results indicate that C. carpio possesses two functional fpns with distinct expression patterns, highlighting the potential for functional divergence and expression differentiation among fpns in this species.
摘要：
铁吸收,运输,储存需要几种蛋白质的参与，包括铁转运蛋白(fpn)，唯一已知的铁外排运输机。由于其临界函数fpn已被研究，特别是在人类中。这里,我们在鲤鱼（CyprinuscarpioL.）中表征了铁转运蛋白基因，并进行了RNA-seq分析以评估其在不同组织中的组成型转录水平。我们的结果表明C.carpio具有两个具有不同表达模式的功能性fpns，突出了该物种中fpns之间功能差异和表达分化的潜力。
