Abstract：
This retrospective study aimed at determining the dimension of the interthalamic adhesion (ITA) in patients with the idiopathic intracranial hypertension (IIH) for assisting in preoperative radiologic diagnosis.
The study universe consisted of magnetic resonance images of 20 patients with IIH (age: 22.70 ± 4.04 years, sex: 14 females and 6 males) and 20 normal subjects (age 22.30± 2.94 years, sex: 14 females and 6 males). To determine the morphology of ITA, its height (vertical diameter) and width (horizontal diameter) were measured on the coronal and axial planes, respectively.
The height and width of ITA in IIH were measured as 2.58 ± 0.71 mm (range: 1.40-4.20 mm) and 2.73 ± 0.77 mm (range: 1.70-4.40 mm), respectively. Its height and width in controls were measured as 4.99 ± 1.04 mm (range: 2.70-6.30 mm) and 4.92 ± 1.11 mm (range: 2.60-6.50 mm), respectively. ITA height and width in IIH was significantly smaller compared with controls (P < 0.001). For an arbitrary cutoff of 3.85 mm, the sensitivity of the height of ITA was 85% with 95% specificity. For an arbitrary cutoff of 4.45 mm, the sensitivity of the width of ITA was 75% with 100% specificity.
The height and width of ITA are approximately 50% smaller in IIH than controls; therefore alterations in the dimension of ITA may be a valuable radiologic sign for the diagnosis of IIH.
The study universe consisted of magnetic resonance images of 20 patients with IIH (age: 22.70 ± 4.04 years, sex: 14 females and 6 males) and 20 normal subjects (age 22.30± 2.94 years, sex: 14 females and 6 males). To determine the morphology of ITA, its height (vertical diameter) and width (horizontal diameter) were measured on the coronal and axial planes, respectively.
The height and width of ITA in IIH were measured as 2.58 ± 0.71 mm (range: 1.40-4.20 mm) and 2.73 ± 0.77 mm (range: 1.70-4.40 mm), respectively. Its height and width in controls were measured as 4.99 ± 1.04 mm (range: 2.70-6.30 mm) and 4.92 ± 1.11 mm (range: 2.60-6.50 mm), respectively. ITA height and width in IIH was significantly smaller compared with controls (P < 0.001). For an arbitrary cutoff of 3.85 mm, the sensitivity of the height of ITA was 85% with 95% specificity. For an arbitrary cutoff of 4.45 mm, the sensitivity of the width of ITA was 75% with 100% specificity.
The height and width of ITA are approximately 50% smaller in IIH than controls; therefore alterations in the dimension of ITA may be a valuable radiologic sign for the diagnosis of IIH.
摘要：
目的：这项回顾性研究旨在确定特发性颅内高压（IIH）患者丘脑粘连（ITA）的大小，以协助术前放射学诊断。
方法：研究范围包括20例IIH患者的磁共振图像（年龄：22.70±4.04岁，性别：14名女性和6名男性）和20名正常受试者（年龄22.30±2.94岁，性别：14名女性和6名男性）。为了确定ITA的形态，它的高度（垂直直径）和宽度（水平直径）在冠状和轴向平面上测量，分别。
结果：IIH中ITA的高度和宽度分别为2.58±0.71mm（范围：1.40-4.20mm）和2.73±0.77mm（范围：1.70-4.40mm），分别。对照组的高度和宽度分别为4.99±1.04mm（范围：2.70-6.30mm）和4.92±1.11mm（范围：2.60-6.50mm），分别。与对照相比,IIH中的ITA高度和宽度显著更小(p<0.001)。对于3.85mm的任意截止值，ITA身高的敏感性为85%,特异性为95%.对于4.45mm的任意截止值，ITA宽度的敏感性为75%,特异性为100%.
结论：IIH中ITA的高度和宽度比对照组小约50％；因此，ITA大小的改变可能是诊断IIH的有价值的放射学标志。
方法：研究范围包括20例IIH患者的磁共振图像（年龄：22.70±4.04岁，性别：14名女性和6名男性）和20名正常受试者（年龄22.30±2.94岁，性别：14名女性和6名男性）。为了确定ITA的形态，它的高度（垂直直径）和宽度（水平直径）在冠状和轴向平面上测量，分别。
结果：IIH中ITA的高度和宽度分别为2.58±0.71mm（范围：1.40-4.20mm）和2.73±0.77mm（范围：1.70-4.40mm），分别。对照组的高度和宽度分别为4.99±1.04mm（范围：2.70-6.30mm）和4.92±1.11mm（范围：2.60-6.50mm），分别。与对照相比,IIH中的ITA高度和宽度显著更小(p<0.001)。对于3.85mm的任意截止值，ITA身高的敏感性为85%,特异性为95%.对于4.45mm的任意截止值，ITA宽度的敏感性为75%,特异性为100%.
结论：IIH中ITA的高度和宽度比对照组小约50％；因此，ITA大小的改变可能是诊断IIH的有价值的放射学标志。
