Abstract：
BACKGROUND: For female breast cancer patients, the psychological status after surgery, especially the social and family psychological-related factors, deserves more attention. This study analyzed the influence of social constraints, social support, social isolation, family conflict, and family emotion expression on depression. At the same time, this study conducted the relationship between the variables and the mechanism of action.
METHODS: We conducted a cross-sectional study and 522 breast cancer patients finished questionnaires consisting of Self-Rating Depression Scale (SDS), General Self-Efficacy Scale (GSES), Multi-Dimensional Scale of Perceived Social Support (MSPSS), Social Constraints Scale-5 (SCS-5), Family Environment Scale (FES), and Lubben Social Network Scale (LSNS-6). Multivariable logical regression was used to explore influencing factors. Pearson\'s correlation, hierarchical regression, and simple slope analysis were conducted to verify the role of self-efficacy.
RESULTS: 71.6% of patients had depressive symptoms. Family contradiction (OR = 10.086), social constraints (OR = 2.522), social isolation (OR = 2.507), and high blood glucose (OR = 2.156) were risk factors of depressive symptoms. Family emotional expression (OR = 0.480), family intimacy (OR = 0.235), and self-efficacy (OR = 0.246) were protective factors against depressive symptoms. The interactive items interpretation quantity were as follows: Contradiction*Self-efficacy (ΔR2 = 2.3%, P < 0.001), Emotional expression*Self-efficacy (ΔR2 = 2.6%, P < 0.001), Intimacy*Self-efficacy (ΔR2 = 1.0%, P = 0.018), Social constraints*Self-efficacy (ΔR2 = 1.0%, P = 0.008), Social networks*Self-efficacy (ΔR2 = 1.0%, P = 0.010), Blood Glucose*Self-efficacy (ΔR2 = 0.6%, P = 0.023). The influence of independent variables on depressive symptoms was gradually decreased in the low, mean, and high groups of self-efficacy.
CONCLUSIONS: Postoperative Chinese breast cancer survivors reported higher depressive symptoms. Social, family, and physiological factors could affect depressive symptoms, in which self-factor played moderator roles.
METHODS: We conducted a cross-sectional study and 522 breast cancer patients finished questionnaires consisting of Self-Rating Depression Scale (SDS), General Self-Efficacy Scale (GSES), Multi-Dimensional Scale of Perceived Social Support (MSPSS), Social Constraints Scale-5 (SCS-5), Family Environment Scale (FES), and Lubben Social Network Scale (LSNS-6). Multivariable logical regression was used to explore influencing factors. Pearson\'s correlation, hierarchical regression, and simple slope analysis were conducted to verify the role of self-efficacy.
RESULTS: 71.6% of patients had depressive symptoms. Family contradiction (OR = 10.086), social constraints (OR = 2.522), social isolation (OR = 2.507), and high blood glucose (OR = 2.156) were risk factors of depressive symptoms. Family emotional expression (OR = 0.480), family intimacy (OR = 0.235), and self-efficacy (OR = 0.246) were protective factors against depressive symptoms. The interactive items interpretation quantity were as follows: Contradiction*Self-efficacy (ΔR2 = 2.3%, P < 0.001), Emotional expression*Self-efficacy (ΔR2 = 2.6%, P < 0.001), Intimacy*Self-efficacy (ΔR2 = 1.0%, P = 0.018), Social constraints*Self-efficacy (ΔR2 = 1.0%, P = 0.008), Social networks*Self-efficacy (ΔR2 = 1.0%, P = 0.010), Blood Glucose*Self-efficacy (ΔR2 = 0.6%, P = 0.023). The influence of independent variables on depressive symptoms was gradually decreased in the low, mean, and high groups of self-efficacy.
CONCLUSIONS: Postoperative Chinese breast cancer survivors reported higher depressive symptoms. Social, family, and physiological factors could affect depressive symptoms, in which self-factor played moderator roles.
摘要：
背景：对于女性乳腺癌患者，手术后的心理状态，特别是社会和家庭心理相关因素，值得更多关注。本研究分析了社会约束的影响，社会支持,社会孤立,家庭冲突,和家庭情感表达对抑郁症的影响。同时,本研究进行了变量与作用机制之间的关系。
方法：我们进行了一项横断面研究，522名乳腺癌患者完成了由抑郁自评量表（SDS）组成的问卷，一般自我效能感量表（GSES），领悟社会支持的多维量表(MSPSS)，社会约束量表-5(SCS-5)，家庭环境量表（FES），和Lubben社交网络量表(LSNS-6)。采用多变量回归分析影响因素。皮尔森的相关性，分层回归，并进行简单的斜率分析以验证自我效能感的作用。
结果：71.6%的患者有抑郁症状。家庭矛盾（OR=10.086），社会约束(OR=2.522)，社会隔离（OR=2.507），高血糖（OR=2.156）是抑郁症状的危险因素。家庭情感表达（OR=0.480），家庭亲密关系（OR=0.235），自我效能(OR=0.246)是抑郁症状的保护因素。交互项目解释量如下：矛盾*自我效能感(ΔR2=2.3%，P<0.001)，情绪表达*自我效能感(ΔR2=2.6%，P<0.001)，亲密关系*自我效能感(ΔR2=1.0%，P=0.018),社会约束*自我效能感(ΔR2=1.0%，P=0.008),社交网络*自我效能感(ΔR2=1.0%，P=0.010),血糖*自我效能感(ΔR2=0.6%，P=0.023)。自变量对抑郁症状的影响在低,意思是，和高自我效能感的群体。
结论：术后中国乳腺癌幸存者报告了较高的抑郁症状。社会,家庭,生理因素会影响抑郁症状，其中自我因素扮演了主持人的角色。
方法：我们进行了一项横断面研究，522名乳腺癌患者完成了由抑郁自评量表（SDS）组成的问卷，一般自我效能感量表（GSES），领悟社会支持的多维量表(MSPSS)，社会约束量表-5(SCS-5)，家庭环境量表（FES），和Lubben社交网络量表(LSNS-6)。采用多变量回归分析影响因素。皮尔森的相关性，分层回归，并进行简单的斜率分析以验证自我效能感的作用。
结果：71.6%的患者有抑郁症状。家庭矛盾（OR=10.086），社会约束(OR=2.522)，社会隔离（OR=2.507），高血糖（OR=2.156）是抑郁症状的危险因素。家庭情感表达（OR=0.480），家庭亲密关系（OR=0.235），自我效能(OR=0.246)是抑郁症状的保护因素。交互项目解释量如下：矛盾*自我效能感(ΔR2=2.3%，P<0.001)，情绪表达*自我效能感(ΔR2=2.6%，P<0.001)，亲密关系*自我效能感(ΔR2=1.0%，P=0.018),社会约束*自我效能感(ΔR2=1.0%，P=0.008),社交网络*自我效能感(ΔR2=1.0%，P=0.010),血糖*自我效能感(ΔR2=0.6%，P=0.023)。自变量对抑郁症状的影响在低,意思是，和高自我效能感的群体。
结论：术后中国乳腺癌幸存者报告了较高的抑郁症状。社会,家庭,生理因素会影响抑郁症状，其中自我因素扮演了主持人的角色。
