PDF(Pubmed)
Abstract：
During the last few decades, bat lyssaviruses have become the topic of intensive molecular and epidemiological investigations. Since ancient times, rhabdoviruses have caused fatal encephalitis in humans which has led to research into effective strategies for their eradication. Modelling of potential future cross-species virus transmissions forms a substantial component of the recent infection biology of rabies. In this article, we summarise the available data on the phylogeography of both bats and lyssaviruses in Europe and the adjacent reg ions, especially in the contact zone between the Palearctic and Ethiopian realms. Within these zones, three bat families are present with high potential for cross-species transmission and the spread of lyssaviruses in Phylogroup II to Europe (part of the western Palearctic). The lack of effective therapies for rabies viruses in Phylogroup II and the most divergent lyssaviruses generates impetus for additional phylogenetic and virological research within this geographical region.
摘要：
在过去的几十年里，蝙蝠病毒已成为密集的分子和流行病学调查的主题。自古以来,弹状病毒已在人类中引起致命的脑炎，这导致了对根除它们的有效策略的研究。对潜在的未来跨物种病毒传播进行建模是最近狂犬病感染生物学的重要组成部分。在这篇文章中,我们总结了欧洲蝙蝠和溶血病毒的系统地理和邻近的reg离子的可用数据，特别是在古北地区和埃塞俄比亚地区之间的接触区。在这些区域内,存在三个蝙蝠家族，它们具有很高的跨物种传播潜力，并且在II型系统群中传播病毒到欧洲（古北西部的一部分）。缺乏有效的治疗狂犬病病毒在系统群II和最不同的裂解病毒为该地理区域内的其他系统发育和病毒学研究提供了动力。
