PDF(Pubmed)
Abstract：
In this case report, real-time neuropsychological testing (RTNT) and music listening were applied for resections in the left temporal-parietal lobe during awake surgery (AS). The case is based on a 66-year-old with glioblastoma and alterations in expressive language and memory deficit. Neuropsychological assessment was run at baseline (2-3 days before surgery), discharge from hospital (2-3 days after surgery), and follow-up (1 month and 3 months). RTNT was started before beginning the anesthetic approach (T0) and during tumor excision (T1 and T2). At T0, T1, and T2 (before performing neuropsychological tests), music listening was applied. Before AS and after music listening, the patient reported a decrease in depression and anxiety. During AS, an improvement was shown in all cognitive parameters collected at T0, T1, and T2. After the excision and music listening, the patient reported a further decrease in depression and anxiety. Three days post surgery, and at follow-ups of one month and three months, the patient reported a further improvement in cognitive aspects, the absence of depression, and a reduction in anxiety symptoms. In conclusion, RTNT has been useful in detecting cognitive function levels during tumor excision. Music listening during AS decreased the patient\'s anxiety and depression symptoms.
摘要：
在这个案例报告中,在清醒手术（AS）期间，对左颞顶叶进行了实时神经心理学测试（RTNT）和音乐聆听。该病例基于一名66岁的胶质母细胞瘤以及表达语言和记忆缺陷的改变。神经心理学评估在基线（手术前2-3天）进行，出院（手术后2-3天），并随访(1个月和3个月)。在开始麻醉方法之前（T0）和肿瘤切除期间（T1和T2）开始RTNT。在T0，T1和T2（在进行神经心理学测试之前），音乐聆听应用。在AS之前和听音乐之后，患者报告抑郁和焦虑减轻.在AS期间，在T0,T1和T2时收集的所有认知参数均显示改善.切除和听音乐后，患者报告抑郁和焦虑进一步减轻.手术后三天,在一个月和三个月的随访中，患者报告认知方面有进一步改善，没有抑郁症，焦虑症状的减轻.总之,RTNT可用于检测肿瘤切除期间的认知功能水平。AS期间听音乐减轻了患者的焦虑和抑郁症状。
