PDF(Pubmed)
Abstract：
Studies have suggested the potential roles of serum macronutrients such as calcium and magnesium in the development of uterine fibroids. The primary objective was to assess the association between serum magnesium and calcium levels and the prevalence of uterine fibroids in women of reproductive age. A cross-sectional study of 194 parity-matched women with or without a sonographic diagnosis of uterine fibroids enrolled at a university teaching hospital in Lagos, Southwest Nigeria. Participants\' sociodemographic, ultrasound, and anthropometric information as well as the estimated serum levels of calcium and magnesium were collected for statistical analyses. This study found significant negative associations between low serum calcium levels and uterine fibroids (adjusted odds ratio = 0.06), uterine size, and the number of fibroid nodules. However, no significant association was observed between serum magnesium levels and uterine fibroids. This study found significant inverse associations between low serum calcium levels and uterine fibroids, uterine size, and the number of fibroid nodules.
摘要：
研究表明，血清大量营养素如钙和镁在子宫肌瘤发展中的潜在作用。主要目的是评估育龄妇女血清镁和钙水平与子宫肌瘤患病率之间的关系。在拉各斯的大学教学医院注册的194名具有或不具有子宫肌瘤超声诊断的胎次匹配妇女的横断面研究，尼日利亚西南部。参与者社会人口统计，超声，收集人体测量信息以及估计的血清钙和镁水平进行统计分析。这项研究发现，低血清钙水平与子宫肌瘤之间存在显着负相关（调整后的比值比=0.06），子宫大小,和肌瘤结节的数量。然而,未观察到血清镁水平与子宫肌瘤之间的显著关联.这项研究发现低血清钙水平与子宫肌瘤之间存在显著的负相关，子宫大小,和肌瘤结节的数量。
