PDF(Pubmed)
Abstract：
Polymelia is an extremely rare congenital anomaly where an individual is born with an abnormally developed extra or supernumerary limb which is generally shrunken and functionless. A case of thoracomelia (a type of polymelia) was observed macroscopically and confirmed radiologically in 1.5 years old boy born in Nepal with an abnormal supernumerary upper limb attached to his back in the thoracic region. The limb was successfully amputated, and the boy had a favorable outcome after surgical treatment, without any adverse effects or impairment. Understanding the embryogenesis of thoracomelia is essential for unraveling the complex mechanisms underlying this condition and potentially aiding in early diagnosis and intervention. This case report and review aims to shed light on the intricate processes governing forelimb formation and their perturbations leading to thoracomelia.
摘要：
Polymelia是一种极为罕见的先天性异常，其中一个人出生时有异常发育的额外或额外肢体，通常会缩小且功能不足。在尼泊尔出生的1.5岁男孩中，在胸部区域的背部附着有异常的多余上肢，在宏观上观察到了一例胸膜（一种多发性），并在放射学上证实了一例。肢体被成功截肢,男孩在手术治疗后取得了良好的结果，没有任何不利影响或损害。了解胸膜的胚胎发生对于揭示这种疾病的复杂机制至关重要，并可能有助于早期诊断和干预。本病例报告和综述旨在阐明控制前肢形成的复杂过程及其导致胸膜炎的扰动。
