Abstract：
The need for novel healthcare treatments and drugs has increased due to the expanding human population, detection of newer diseases, and looming pandemics. The development of nanotechnology offers a platform for cutting-edge in vivo non-invasive monitoring and point-of-care-testing (POCT) for rehabilitative disease detection and management. The advancement and uses of nanobiosensors are currently becoming more common in a variety of scientific fields, such as environmental monitoring, food safety, biomedical, clinical, and sustainable healthcare sciences, since the advent of nanotechnology. The identification and detection of biological patterns connected to any type of disease (communicable or not) have been made possible in recent years by several sensing techniques utilizing nanotechnology concerning biosensors and nanobiosensors. In this work, 2218 articles are drawn and screened from six digital databases out of which 17 were shortlisted for this review by using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) technique. As a result, this study uses a systematic methodology to review some recently developed extremely sensitive nanobiosensors, along with their biomedical, point-of-care diagnostics (POCD), or healthcare applications and their capabilities, particularly for the prediction of some fatal diseases based on a few of the most recent publications. The potential of nanobiosensors for medicinal, therapeutic, or other sustainable healthcare applications, notably for ailments diagnostics, is also recognized as a way forward in the manifestation of future trends.
摘要：
由于不断扩大的人口，对新型医疗保健治疗和药物的需求增加了。检测新的疾病，和迫在眉睫的流行病。纳米技术的发展为尖端的体内非侵入性监测和即时检测（POCT）提供了一个平台，用于康复疾病的检测和管理。纳米生物传感器的进步和用途目前在各种科学领域变得越来越普遍，如环境监测，食品安全,生物医学,临床,和可持续医疗保健科学，自从纳米技术出现以来。近年来，通过利用有关生物传感器和纳米生物传感器的纳米技术的几种传感技术，可以识别和检测与任何类型的疾病（可传播或非传播）有关的生物模式。在这项工作中,通过使用系统审查和荟萃分析（PRISMA）技术的首选报告项目，从六个数字数据库中抽取和筛选了2218篇文章，其中17篇入围了本次审查。因此,这项研究使用了系统的方法来回顾一些最近开发的极其敏感的纳米生物传感器，以及他们的生物医学，即时诊断（POCD），或医疗保健应用程序及其功能，特别是根据一些最新出版物对一些致命疾病的预测。纳米生物传感器的潜在药用，治疗性的,或其他可持续医疗应用，特别是对疾病的诊断，也被认为是未来趋势的体现。
