关键词: MRI Meniere’s disease endolymphatic hydrops immune and inflammatory responses pathophysiology

来  源:   DOI:10.3389/fneur.2023.1220162   PDF(Pubmed)

Abstract:
UNASSIGNED: The primary objective of this study was to present the progressive changes from labyrinthitis to endolymphatic hydrops (EH) demonstrated in the inner ear MRI of a patient with MD and suspected immune dysfunction.
UNASSIGNED: This 31-year-old male was diagnosed with MD and suspected autoimmune diseases.
UNASSIGNED: Immunosuppressants and biological agents.
UNASSIGNED: Inner ear MRI images.
UNASSIGNED: Changes in the patient\'s progress revealed that inner ear immune and inflammatory changes might induce EH, which may eventually turn into MD.
UNASSIGNED: This case is the first documented case of MRI revealing progressive changes from inflammatory response to endolymphatic hydrops in the inner ear. It shows the correlation between MD and inflammation visually. It is of great significance to reveal the pathogenesis of MD to further assist in the guidance of treatment decision making.
摘要:
这项研究的主要目的是介绍在患有MD和疑似免疫功能障碍的患者的内耳MRI中显示的从迷路炎到内淋巴积水(EH)的进行性变化。
这位31岁的男性被诊断患有MD和疑似自身免疫性疾病。
免疫抑制剂和生物制剂。
内耳MRI图像。
患者进展的变化表明内耳免疫和炎症的变化可能会诱发EH,最终可能会变成MD。
该病例是第一个有记录的MRI病例,显示内耳内淋巴积水的炎症反应进行性变化。它在视觉上显示MD与炎症之间的相关性。揭示MD的发病机制对进一步辅助指导治疗决策具有重要意义。
公众号