Abstract：
Chondroblastoma is a rare benign cartilaginous tumor mostly confined to the epiphyses and apophyses. Cases outside the epiphyseal region are exceedingly rare. Extramedullary chondroblastomas are exceptional; to our knowledge, only two cases qualified as \"periosteal chondroblastoma\" have been described in the literature. We report two cases of metaphyseal periosteal chondroblastoma both located on the inferior surface of the femoral neck. Both cases were paucicellular with an unusual dense sclerotic reaction. The diagnosis of chondroblastoma was supported by the expression of histone 3.3, K36M mutant in tumor cells.
摘要：
软骨母细胞瘤是一种罕见的良性软骨肿瘤，主要局限于骨phy和骨hy。骨phy区以外的病例极为罕见。髓外软骨母细胞瘤是特殊的；据我们所知，文献中只有两例符合“骨膜软骨母细胞瘤”的病例。我们报告了两例均位于股骨颈下表面的干phy端骨膜软骨母细胞瘤。两例均为少细胞，伴有异常的致密硬化反应。肿瘤细胞中组蛋白3.3，K36M突变体的表达支持软骨母细胞瘤的诊断。
