Abstract：
Autoimmune neurological diseases (ANDs) are a specific type of autoimmune disease that affect cells within the central and peripheral nervous system. ANDs trigger various physical/neuropsychiatric symptoms. However, language impairments in people with ANDs are not well characterized. Here we aimed to determine the kinds of language impairment that most commonly emerge in 10 ANDs, the characteristics of the patients (demographic, neurological damage), and the assessment methods used.
We followed the PRISMA Extension for Scoping Reviews (PRISMA-ScR). PubMed and Google Scholar were searched. We used a list of search terms containing 10 types of ANDs (e.g., multiple sclerosis, acute disseminated encephalomyelitis) in combination with the terms aphasia, dysphasia, fluency, language, listening, morphology, phonology, pragmatics, reading, semantics, speaking, syntax, writing. The reference lists and citations of the relevant papers were also investigated. The type of AND, patient characteristics, neurological damage and examination technique, language tests administered, and main findings were noted for each study meeting the inclusion criteria.
We found 171 studies meeting our inclusion criteria. These comprised group studies and case studies. Language impairments differed largely among types of ANDs. Neurological findings were mentioned in most of the papers, but specific language tests were rarely used.
Language symptoms in people with ANDs are commonly reported. These are often not full descriptions or only focus on specific time points in the course of the disease. Future research needs to assess specific language functions in people with ANDs and relate their language impairments to brain damage at different stages of disease evolution.
We followed the PRISMA Extension for Scoping Reviews (PRISMA-ScR). PubMed and Google Scholar were searched. We used a list of search terms containing 10 types of ANDs (e.g., multiple sclerosis, acute disseminated encephalomyelitis) in combination with the terms aphasia, dysphasia, fluency, language, listening, morphology, phonology, pragmatics, reading, semantics, speaking, syntax, writing. The reference lists and citations of the relevant papers were also investigated. The type of AND, patient characteristics, neurological damage and examination technique, language tests administered, and main findings were noted for each study meeting the inclusion criteria.
We found 171 studies meeting our inclusion criteria. These comprised group studies and case studies. Language impairments differed largely among types of ANDs. Neurological findings were mentioned in most of the papers, but specific language tests were rarely used.
Language symptoms in people with ANDs are commonly reported. These are often not full descriptions or only focus on specific time points in the course of the disease. Future research needs to assess specific language functions in people with ANDs and relate their language impairments to brain damage at different stages of disease evolution.
摘要：
背景：自身免疫性神经系统疾病（ANDs）是一种特定类型的自身免疫性疾病，会影响中枢神经系统和周围神经系统内的细胞。ANDs会引发各种身体/神经精神症状。然而,患有AND的人的语言障碍没有得到很好的表征。在这里，我们的目标是确定在10个AND中最常见的语言障碍类型，患者的特征(人口统计，神经损伤)，以及使用的评估方法。
方法：我们遵循PRISMA扩展范围审查（PRISMA-ScR）。搜索了PubMed和GoogleScholar。我们使用了包含10种类型的AND的搜索词列表(例如，多发性硬化症,急性播散性脑脊髓炎）与失语症，吞咽困难,流利,语言,听,形态学,语音学,语用学,阅读,语义，说话,语法,writing.还调查了相关论文的参考文献清单和引文。AND的类型,患者特征,神经损伤和检查技术，语言测试管理，并记录了符合纳入标准的每项研究的主要发现。
结果：我们发现171项研究符合我们的纳入标准。这些包括小组研究和案例研究。不同类型的AND之间的语言障碍差异很大。大多数论文都提到了神经学的发现，但是很少使用特定的语言测试。
结论：通常报告有ANDs患者的语言症状。这些通常不是完整的描述，或仅关注疾病过程中的特定时间点。未来的研究需要评估患有AND的人的特定语言功能，并将他们的语言障碍与疾病演变的不同阶段的脑损伤联系起来。
方法：我们遵循PRISMA扩展范围审查（PRISMA-ScR）。搜索了PubMed和GoogleScholar。我们使用了包含10种类型的AND的搜索词列表(例如，多发性硬化症,急性播散性脑脊髓炎）与失语症，吞咽困难,流利,语言,听,形态学,语音学,语用学,阅读,语义，说话,语法,writing.还调查了相关论文的参考文献清单和引文。AND的类型,患者特征,神经损伤和检查技术，语言测试管理，并记录了符合纳入标准的每项研究的主要发现。
结果：我们发现171项研究符合我们的纳入标准。这些包括小组研究和案例研究。不同类型的AND之间的语言障碍差异很大。大多数论文都提到了神经学的发现，但是很少使用特定的语言测试。
结论：通常报告有ANDs患者的语言症状。这些通常不是完整的描述，或仅关注疾病过程中的特定时间点。未来的研究需要评估患有AND的人的特定语言功能，并将他们的语言障碍与疾病演变的不同阶段的脑损伤联系起来。
