Abstract：
AQP4-IgG NMOSD (anti-aquaporin-4 neuromyelitis optica spectrum disorder) and MOGAD (myelin oligodendrocyte glycoprotein antibody associated disease) are unique disorders among themselves, with rare reports of dual seropositivity being described. Evaluation with cell-based assays reduces the incidence of false positivity. The clinical features of these cases may either have a dominant phenotype or may evolve into one subsequently. We describe a young girl aged 18-year-old who presented with longitudinally extensive transverse myelitis and dual seropositivity to both AQP4 and MOG antibodies.
摘要：
AQP4-IgGNMOSD（抗水通道蛋白-4视神经脊髓炎谱系障碍）和MOGAD（髓鞘少突胶质细胞糖蛋白抗体相关疾病）是它们之间独特的疾病，罕见的双重血清阳性报告被描述。使用基于细胞的测定的评估降低了假阳性的发生率。这些病例的临床特征可能具有显性表型，也可能随后演变成显性表型。我们描述了一个18岁的年轻女孩，她表现出纵向广泛的横贯性脊髓炎和AQP4和MOG抗体的双重血清阳性。
