{Reference Type}: Journal Article
{Title}: Double hit - A case in point for dual seropositivity to AQP4 and MOG antibodies.
{Author}: Jain K;Anita M;Netravathi M;
{Journal}: J Neuroimmunol
{Volume}: 383
{Issue}: 0
{Year}: 2023 Oct 15
{Factor}: 3.221
{DOI}: 10.1016/j.jneuroim.2023.578198
{Abstract}: AQP4-IgG NMOSD (anti-aquaporin-4 neuromyelitis optica spectrum disorder) and MOGAD (myelin oligodendrocyte glycoprotein antibody associated disease) are unique disorders among themselves, with rare reports of dual seropositivity being described. Evaluation with cell-based assays reduces the incidence of false positivity. The clinical features of these cases may either have a dominant phenotype or may evolve into one subsequently. We describe a young girl aged 18-year-old who presented with longitudinally extensive transverse myelitis and dual seropositivity to both AQP4 and MOG antibodies.