Articles published between January 2005 and March 2022 were searched in MEDLINE, CINAHL, and Scopus. Studies that included KD in lifestyle interventions for adults with T2D and overweight/obesity and measured ketone levels were included.
The eleven included studies comprised eight randomized controlled trials. They mainly used self-reported measures to evaluate adherence to the KD and level of PA. We found studies reported higher carbohydrate intake and lower fat intake than the KD regimen. Great inconsistencies were found among studies on the measurement and reporting of ketone and PA levels.
Our results demonstrated the need to develop intervention strategies to improve adherence to the KD, as well as the necessity of developing standardized diet and PA assessment tools to establish a stronger evidence base for including KD in lifestyle interventions for weight and T2D management among adults with overweight/obesity and T2D.
方法:在2005年1月至2022年3月之间发表的文章在MEDLINE中进行了搜索,CINAHL,还有Scopus.纳入了将KD纳入T2D和超重/肥胖成人生活方式干预的研究,并测量了酮水平。
结果:11项纳入研究包括8项随机对照试验。他们主要使用自我报告的措施来评估对KD的依从性和PA水平。我们发现,与KD方案相比,研究报告了更高的碳水化合物摄入量和更低的脂肪摄入量。在酮和PA水平的测量和报告研究中发现了很大的不一致之处。
结论:我们的研究结果表明,需要制定干预策略来提高对KD的依从性,以及开发标准化饮食和PA评估工具的必要性,以建立更强大的证据基础,将KD纳入超重/肥胖和T2D成人体重和T2D管理的生活方式干预措施。