PDF(Pubmed)
Abstract：
Intestinal microsporidiosis is most often caused by Enterocytozoon bieneusi, and to a lesser extent by species of the genus Encephalitozoon. Until now, Encephalitozoon hellem was not clearly known to induce disease restricted to the intestine, or rarely in HIV subjects or in tropical countries. We report here 11 cases of delineated intestinal microsporidioses due to E. hellem diagnosed in France in non-HIV patients. Briefly, all patients were immunocompromised. They all suffered from diarrhoea, associated in nearly 50% of cases with weight loss. Concerning treatment, 5/11 patients had a discontinuation or a decrease of their immunosuppressive therapy, and 4/11 received albendazole. All patients recovered. Five different genotypes were identified based on the rRNA ITS sequence.
摘要：
摘要肠道微孢子虫病最常见的原因是肠孢子虫，在较小程度上是由头孢菌素属的物种引起的。直到现在,尚不清楚清楚会导致仅限于肠道的疾病，或很少在艾滋病毒受试者或热带国家。我们在这里报告了11例由于法国在非HIV患者中诊断出的E.hellem引起的肠道微孢子虫病。简而言之，所有患者免疫功能低下.他们都患有腹泻，近50%的病例与体重减轻有关。关于治疗，5/11患者停止或减少他们的免疫抑制治疗，4/11接受阿苯达唑。所有患者均康复。基于rRNAITS序列鉴定了五种不同的基因型。
