Abstract：
Background: A clinician\'s choice of stereotest is influenced by the robustness of the measurement, in terms of sensitivity, specificity and test-retest variability. In relation to the latter aspect, there are limited data on the test-retest variability of these new tests and how they compare to the more commonly used stereotests. Therefore, the aim of the study was to determine the test-retest variability of four different measures of stereoacuity (TNO, Frisby, Lang Stereopad and Asteroid (Accurate STEReotest On a mobIle Device)) and to compare the stereoacuity measurements between the tests in an adult population. Methods: Stereoacuity was measured twice using TNO, Frisby, Lang Stereopad and Asteroid. Inclusion criteria included adult participants (18 years and older), no known ophthalmic condition and VA (Visual Acuity) equal to or better than 0.3 logMAR (Logarithm of the Minimum Angle of Resolution) with interocular difference of less than 0.2 logMAR. Bland-Altman analysis was used to assess agreement within and between stereotests. Differences in stereo thresholds were compared using signed Wilcoxon tests. Results: Fifty-four adults (male: 23 and female: 31) with VA equal to or better than 0.3 logMAR in either eye and interocular difference less than 0.2 logMAR were assessed (mean age: 38 years, SD: 12.7, range: 18-72). The test-retest variability of all the clinical stereotests, with the exception of the Lang Stereopad (p = .03, Wilcoxon signed-rank test), was clinically insignificant as the mean bias was equal or less than 0.06 log seconds of arc (equivalent to 1.15 seconds of arc). While the Asteroid test had the smallest variation between repeated measures (mean bias: -0.01 log seconds of arc), the Frisby and Lang Stereopad tests had the narrowest and widest limits of agreement respectively. When comparing results between tests, the biggest mean bias was between Frisby and Lang Stereopad (-0.62 log seconds of arc), and 64.8% and 31.5% of differences were in the medium (21-100\" of arc) and larger (>100\" of arc) ranges respectively. Conclusion: The TNO and Frisby tests have good reliability but measure stereoacuity over a narrower range compared to the Asteroid which shows less variation on repeated testing but has a larger testing range. The data reported here show varying degrees of agreement in a cohort of visually normal participants, and further investigation is required to determine if there is further variability when stereoacuity is reduced.
摘要：
背景：临床医生对立体测试的选择受到测量的鲁棒性的影响，在灵敏度方面，特异性和重测变异性。关于后一方面，关于这些新测试的测试-重测变异性以及它们与更常用的立体测试相比的数据有限。因此,研究的目的是确定四种不同立体视敏度测量的重测变异性(TNO，Frisby,LangStereopad和Asteroid（在mobile设备上进行准确的定向测试）），并比较成年人群测试之间的立体敏锐度测量值。方法：使用TNO两次测量立体视力，Frisby,朗立体声和小行星。纳入标准包括成年参与者（18岁及以上），没有已知的眼科状况和VA（视力）等于或优于0.3logMAR（最小分辨率角度的对数），眼间差异小于0.2logMAR。Bland-Altman分析用于评估立体测试内部和之间的协议。使用符号Wilcoxon检验比较立体阈值的差异。结果：评估了54名成年人（男性：23岁，女性：31），其中两眼的VA等于或优于0.3logMAR，并且眼间差异小于0.2logMAR（平均年龄：38岁，SD：12.7，范围：18-72）。所有临床立体测试的重测变异性，除了LangStereopad（p=.03，Wilcoxon符号秩检验），在临床上不显著，因为平均偏差等于或小于0.06log秒的弧（相当于1.15秒的弧）。虽然小行星测试在重复测量之间的变化最小(平均偏差:-0.01对数秒弧)，Frisby和LangStereopad测试分别具有最窄和最宽的协议限制。当比较测试之间的结果时，最大的平均偏差在Frisby和LangStereopad之间(-0.62对数弧秒)，差异的64.8%和31.5%分别在中等(21-100"弧度)和较大(>100"弧度)范围内。结论：与小行星相比，TNO和Frisby测试具有良好的可靠性，但在较窄的范围内测量立体视敏度，后者在重复测试中显示出较小的变化，但测试范围更大。这里报告的数据显示，在一组视觉正常的参与者中，不同程度的一致性，并且需要进一步调查以确定当立体敏锐度降低时是否存在进一步的变异性。
