PDF(Pubmed)
Abstract：
The case at hand involves a 25-year-old woman suffering from a gradual enlargement of a gluteal mass over a five-year period. This rare medical condition is classified as superficial CD34-positive fibroblastic tumor (SCPFT), an intermediate form of mesenchymal malignancy, originally identified in medical literature in 2014. Initial physical examination revealed a 10 x 10 cm lump in the right upper gluteal region. Magnetic resonance imaging demonstrated a well-circumscribed lesion within the right gluteus maximus muscle. The patient had the lump removed surgically. Examination under a microscope revealed tumor cells with extensive pleomorphism, high cytokeratin (CK) and CD34 positivity, and a low Ki67 index, all of which are consistent with SCPFT. Postoperatively, the patient showed marked improvement, and ongoing monitoring was initiated due to the potential for local recurrence. This case reinforces the importance of considering SCPFT in the differential diagnosis of soft tissue masses, emphasizing the role of immunohistochemical staining in reaching a correct diagnosis. Given the rarity of SCPFT, more studies are necessary to refine our understanding and treatment approaches.
摘要：
手头的案件涉及一名25岁的妇女，在五年的时间里，臀部肿块逐渐增大。这种罕见的疾病被归类为浅表CD34阳性成纤维细胞肿瘤（SCPFT），间充质恶性肿瘤的一种中间形式，最初在2014年的医学文献中发现。最初的体格检查显示右上臀区有一个10x10厘米的肿块。磁共振成像显示右臀大肌内有明确的病变。患者通过手术切除了肿块。显微镜下检查发现肿瘤细胞具有广泛的多态性，高细胞角蛋白（CK）和CD34阳性，和低Ki67指数，所有这些都与SCPFT一致。术后,病人表现出明显的改善，并且由于有可能出现局部复发,因此开始了持续监测.该病例强调了在软组织肿块的鉴别诊断中考虑SCPFT的重要性，强调免疫组织化学染色在达到正确诊断中的作用。鉴于SCPFT的稀有性，需要更多的研究来完善我们的理解和治疗方法。
