PDF(Pubmed)
Abstract：
The continuous evolution of cancer biology has led to the discovery of mammaglobin, a potential novel biomarker for breast carcinoma. This review aims to unravel the enigmatic aspects of mammaglobin and elucidate its potential role in redefining the paradigm of breast carcinoma biomarkers. We will thoroughly examine its expression in tumoral and peritumoral tissues and its circulating levels in the blood, thereby providing insights into its possible function in cancer progression and metastasis. Furthermore, the potential application of mammaglobin as a non-invasive diagnostic tool and a target for personalized treatment strategies will be discussed. Given the increasing incidence of breast carcinoma worldwide, the exploration of novel biomarkers such as mammaglobin is crucial in advancing our diagnostic capabilities and treatment modalities, ultimately contributing to improved patient outcomes.
摘要：
癌症生物学的不断发展导致了乳腺球蛋白的发现，一个潜在的新的乳腺癌生物标志物。这篇综述旨在解开乳腺球蛋白的神秘方面，并阐明其在重新定义乳腺癌生物标志物范式中的潜在作用。我们将彻底检查其在肿瘤和肿瘤周围组织中的表达及其在血液中的循环水平，从而为其在癌症进展和转移中的可能功能提供了见解。此外，我们将讨论乳腺球蛋白作为非侵入性诊断工具和个性化治疗策略的目标的潜在应用.鉴于全球乳腺癌的发病率不断上升，新的生物标志物如乳腺球蛋白的探索对于提高我们的诊断能力和治疗方式至关重要，最终有助于改善患者预后。
