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Abstract：
Hepatic inflammatory pseudotumors (IPTs) are defined as benign, non-malignant, non-metastasizing tumors characterized by the presence of myofibroblastic spindle cells, hetorogenous populations of inflammatory cells, particularly plasma cells, lymphocytes and macrophages, as well as locations of fibrosis and necrosis without cellular anaplasia or atypical mitoses. Despite subsequent reports in the references, hepatic IPT remains difficult to diagnose; while posing major issues specifically for its differential diagnosis compared with that of other various benign diseases and malignant hepatic tumors. Histopathological findings are always a requisite for confirming the diagnosis, particularly given that the pathogenesis of IPT remains ambiguous to date. Hepatic IPT is a heterogeneous entity in terms of its clinical features, pathological findings, and pathogenesis. Once the diagnosis is confirmed, however, needless surgery such as wedge resection and lobectomy should be avoided. Here, we discuss the heterogeneity of hepatic IPT, its clinical features, pathological findings, and pathogenesis, and describe its differential diagnosis.
摘要：
肝脏炎性假瘤（IPT）被定义为良性，非恶性,以肌纤维母细胞梭形细胞为特征的非转移性肿瘤，炎症细胞的异源性群体，特别是浆细胞，淋巴细胞和巨噬细胞，以及纤维化和坏死的位置，没有细胞间变或非典型有丝分裂。尽管参考文献中有随后的报道，肝脏IPT仍然难以诊断；与其他各种良性疾病和恶性肝肿瘤相比，其鉴别诊断存在重大问题。组织病理学检查结果始终是确认诊断的必要条件，特别是考虑到IPT的发病机制至今仍不明确。肝脏IPT在其临床特征方面是一种异质实体，病理结果，和发病机制。一旦确诊,然而,应避免不必要的手术，如楔形切除术和肺叶切除术。这里,我们讨论了肝脏IPT的异质性，其临床特征，病理结果，和发病机制，并描述其鉴别诊断。
