关键词: closed-loop systems drug delivery systems feedback stimulation high-precision therapeutics implantable therapeutics personalized healthcare soft bioelectronics wearable therapeutics

Mesh : Humans Precision Medicine Electronics, Medical Wearable Electronic Devices

来  源:   DOI:10.1021/acsnano.3c02513

Abstract:
Soft bioelectronics play an increasingly crucial role in high-precision therapeutics due to their softness, biocompatibility, clinical accuracy, long-term stability, and patient-friendliness. In this review, we provide a comprehensive overview of the latest representative therapeutic applications of advanced soft bioelectronics, ranging from wearable therapeutics for skin wounds, diabetes, ophthalmic diseases, muscle disorders, and other diseases to implantable therapeutics against complex diseases, such as cardiac arrhythmias, cancer, neurological diseases, and others. We also highlight key challenges and opportunities for future clinical translation and commercialization of soft therapeutic bioelectronics toward personalized medicine.
摘要:
软生物电子学由于其柔软性在高精度治疗中起着越来越重要的作用,生物相容性,临床准确性,长期稳定,和耐心友好。在这次审查中,我们全面概述了先进的软生物电子学的最新代表性治疗应用,从皮肤伤口的可穿戴疗法,糖尿病,眼科疾病,肌肉疾病,和其他疾病对复杂疾病的可植入疗法,比如心律失常,癌症,神经系统疾病,和其他人。我们还强调了软治疗生物电子学未来临床转化和商业化向个性化医疗的关键挑战和机遇。
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