PDF(Pubmed)
Abstract：
OBJECTIVE: To investigate the color stability of light-cured (LC) restorative material in different pediatric drug formulations.
METHODS: Two distinct restorative materials, specifically LC resin and LC glass ionomer cement (GIC), were employed to create 88 disc-shaped specimens. These comprised 44 specimens fabricated from each material. Each specimen had a diameter of 5 mm and a height of 3 mm. To conduct the experiment, specimens were randomly allocated into four experimental groups, each containing 11 specimens made of each material. This division was accomplished through the use of a stratified random sampling method. The five experimental groups and their respective liquid medications were as follows: Group 1 - montelukast sodium and levocetirizine dihydrochloride syrup, Group 2 - cefixime, Group 3 - sodium valproate, and Group 4 - metronidazole. To ensure thorough exposure to the medications, all samples underwent a two-minute agitation cycle, which was repeated every 12 h over the course of one week. Following the immersion period, the color stability of all specimens was assessed using a spectrophotometer. The data obtained from the color stability measurements were subjected to statistical analysis using one-way analysis of variance (ANOVA), followed by a post hoc test. The aim was to determine whether significant differences in color stability were observed among the groups studied.
RESULTS: The mean values and standard deviations of ΔE were calculated. The highest values of ΔE were observed in Group 3 (4.70 ± 1.89), followed by Group 4 (4.04 ± 2.10). Conversely, the lowest ΔE values were observed in Group 2 (3.23 ± 2.02) and Group 1 (3.24 ± 2.31). The calculated p-value was 0.298, and the F-value was 1.269.
CONCLUSIONS: This study concludes that both restorative materials, LC composite and LC GIC, are susceptible to discoloration. Sodium valproate exhibited the greatest staining effect on both materials. Conversely, cefixime had the least impact on the color of the LC composite, whereas montelukast had the least effect on the color of LC GIC.
METHODS: Two distinct restorative materials, specifically LC resin and LC glass ionomer cement (GIC), were employed to create 88 disc-shaped specimens. These comprised 44 specimens fabricated from each material. Each specimen had a diameter of 5 mm and a height of 3 mm. To conduct the experiment, specimens were randomly allocated into four experimental groups, each containing 11 specimens made of each material. This division was accomplished through the use of a stratified random sampling method. The five experimental groups and their respective liquid medications were as follows: Group 1 - montelukast sodium and levocetirizine dihydrochloride syrup, Group 2 - cefixime, Group 3 - sodium valproate, and Group 4 - metronidazole. To ensure thorough exposure to the medications, all samples underwent a two-minute agitation cycle, which was repeated every 12 h over the course of one week. Following the immersion period, the color stability of all specimens was assessed using a spectrophotometer. The data obtained from the color stability measurements were subjected to statistical analysis using one-way analysis of variance (ANOVA), followed by a post hoc test. The aim was to determine whether significant differences in color stability were observed among the groups studied.
RESULTS: The mean values and standard deviations of ΔE were calculated. The highest values of ΔE were observed in Group 3 (4.70 ± 1.89), followed by Group 4 (4.04 ± 2.10). Conversely, the lowest ΔE values were observed in Group 2 (3.23 ± 2.02) and Group 1 (3.24 ± 2.31). The calculated p-value was 0.298, and the F-value was 1.269.
CONCLUSIONS: This study concludes that both restorative materials, LC composite and LC GIC, are susceptible to discoloration. Sodium valproate exhibited the greatest staining effect on both materials. Conversely, cefixime had the least impact on the color of the LC composite, whereas montelukast had the least effect on the color of LC GIC.
摘要：
目的：研究光固化（LC）修复材料在不同儿科药物配方中的颜色稳定性。
方法：两种不同的修复材料，特别是LC树脂和LC玻璃离聚物水泥(GIC)，用于创建88个圆盘形标本。这些包括由每种材料制成的44个样本。每个样品具有5mm的直径和3mm的高度。为了进行实验，标本随机分为四个实验组，每个包含11个由每种材料制成的标本。这种划分是通过使用分层随机抽样方法完成的。五个实验组及其各自的液体药物如下：第1组-孟鲁司特钠和左西替利嗪二盐酸盐糖浆，第2组-头孢克肟，第3组-丙戊酸钠，和第4组-甲硝唑。为了确保彻底接触药物，所有样品都经历了两分钟的搅拌周期，在一周的过程中每12小时重复一次。在浸泡期之后，使用分光光度计评估所有样品的颜色稳定性。使用单向方差分析(ANOVA)对从颜色稳定性测量获得的数据进行统计分析。然后是事后测试。目的是确定在所研究的组中是否观察到颜色稳定性的显著差异。
结果:计算ΔE的平均值和标准偏差。在第3组中观察到ΔE的最高值（4.70±1.89），其次是第4组(4.04±2.10)。相反，在第2组（3.23±2.02）和第1组（3.24±2.31）中观察到最低的ΔE值。计算的p值为0.298,F值为1.269。
结论：这项研究得出的结论是，两种修复材料，LC复合和LCGIC，容易变色。丙戊酸钠对两种材料均表现出最大的染色效果。相反，头孢克肟对LC复合材料的颜色影响最小，而孟鲁司特对LCGIC的颜色影响最小。
方法：两种不同的修复材料，特别是LC树脂和LC玻璃离聚物水泥(GIC)，用于创建88个圆盘形标本。这些包括由每种材料制成的44个样本。每个样品具有5mm的直径和3mm的高度。为了进行实验，标本随机分为四个实验组，每个包含11个由每种材料制成的标本。这种划分是通过使用分层随机抽样方法完成的。五个实验组及其各自的液体药物如下：第1组-孟鲁司特钠和左西替利嗪二盐酸盐糖浆，第2组-头孢克肟，第3组-丙戊酸钠，和第4组-甲硝唑。为了确保彻底接触药物，所有样品都经历了两分钟的搅拌周期，在一周的过程中每12小时重复一次。在浸泡期之后，使用分光光度计评估所有样品的颜色稳定性。使用单向方差分析(ANOVA)对从颜色稳定性测量获得的数据进行统计分析。然后是事后测试。目的是确定在所研究的组中是否观察到颜色稳定性的显著差异。
结果:计算ΔE的平均值和标准偏差。在第3组中观察到ΔE的最高值（4.70±1.89），其次是第4组(4.04±2.10)。相反，在第2组（3.23±2.02）和第1组（3.24±2.31）中观察到最低的ΔE值。计算的p值为0.298,F值为1.269。
结论：这项研究得出的结论是，两种修复材料，LC复合和LCGIC，容易变色。丙戊酸钠对两种材料均表现出最大的染色效果。相反，头孢克肟对LC复合材料的颜色影响最小，而孟鲁司特对LCGIC的颜色影响最小。
