关键词: Cirrhosis Drugs: infectious diseases Infection (gastroenterology) Malignant disease and immunosuppression Transplantation

Mesh : Humans Liver Transplantation / adverse effects Mucormycosis / diagnosis drug therapy etiology Living Donors Cognition Fatal Outcome

来  源:   DOI:10.1136/bcr-2022-253460   PDF(Pubmed)

Abstract:
Gastrointestinal mucormycosis (GIM) is an uncommonly encountered fungal infection following solid-organ transplantation. GIM is known to be associated with immunocompromised states, remains difficult to diagnose and often results in fatal outcomes. It is plausibly the delay in initiation of appropriate treatment strategies that leads to failure of response and patient demise. We report two cases of GIM following live donor liver transplantation, presenting with bleeding and perforation, respectively, highlighting the challenges in making a timely diagnosis of mucormycosis, particularly in immunocompromised patients.
摘要:
胃肠道毛霉菌病(GIM)是实体器官移植后罕见的真菌感染。已知GIM与免疫受损状态有关,仍然难以诊断,并且经常导致致命的结果。合理的是,延迟启动适当的治疗策略会导致反应失败和患者死亡。我们报告了2例GIM活体肝移植后,出现出血和穿孔,分别,突出了及时诊断毛霉菌病的挑战,特别是在免疫功能低下的患者中。
公众号