UNASSIGNED: Seven eyes of 7 patients with unilateral posterior interstitial keratitis were examined by slit-lamp biomicroscopy, anterior segment optical coherence tomography (AS-OCT), and in vivo confocal microscopy (IVCM). The imaging features of the cornea were evaluated and analyzed.
UNASSIGNED: By slit-lamp examination, the posterior corneal stromal opacities were observed in all 7 eyes, and deep neovascularization in 4 eyes. The posterior stromal opacities showed higher reflectivity with an intact overlying epithelium by AS-OCT and did not invade the Bowman\'s layer in all cases. IVCM revealed highly reflective dispersed microdots, needle-shaped bodies, and increased reflectivity of keratocytes in the lesion site in all patients. Active Langerhans cells and an attenuated subbasal nerve plexus were observed in 5 eyes. After treatment, the active Langerhans cells disappeared; however, highly reflective microdots and needle-shaped bodies remained.
UNASSIGNED: The three-dimensional evaluation of slit-lamp biomicroscopy, AS-OCT, and IVCM may help in the early diagnosis of patients with posterior interstitial keratitis.
■通过裂隙灯生物显微镜检查7例单侧后间质性角膜炎患者的7只眼,眼前节光学相干断层扫描(AS-OCT),和体内共聚焦显微镜(IVCM)。对角膜的影像学特征进行评价和分析。
■通过裂隙灯检查,所有7只眼均观察到角膜后基质混浊,和4只眼睛的深层新生血管形成。通过AS-OCT,后部基质混浊显示出较高的反射率,完整的上覆上皮,并且在所有情况下都没有侵入Bowman层。IVCM揭示了高反射分散的微点,针状体,所有患者病变部位的角膜细胞反射率均增加。在5只眼中观察到活跃的朗格汉斯细胞和减弱的基底下神经丛。治疗后,活跃的朗格汉斯细胞消失了;然而,高反射的微点和针状体仍然存在。
■裂隙灯生物显微镜的三维评价,AS-OCT,IVCM可能有助于后间质性角膜炎患者的早期诊断。