PDF(Pubmed)
Abstract：
This report presents anatomo-histopathological, immunohistochemical and molecular analyses of an asymptomatic female dog naturally infected with Leishmania (Leishmania) infantum and her four pups. In addition to routine serological tests, the mother\'s positivity was confirmed by real-time PCR of a bone marrow sample; the placenta and ovaries, however, were negative with the same analysis. The pups presented no positivity in any of the techniques used. It is suggested that the gestational period and factors related to the female\'s immunological condition cause greater variability in the occurrence of vertical infection.
摘要：
本报告介绍了解剖学组织病理学，对自然感染利什曼原虫（Leishmania）婴儿的无症状雌性狗及其四只幼犬进行免疫组织化学和分子分析。除了常规的血清学检测，通过骨髓样本的实时PCR证实了母亲的阳性；胎盘和卵巢，然而,相同的分析结果为阴性。幼犬在使用的任何技术中都没有阳性。提示妊娠期和与女性免疫状况相关的因素导致垂直感染发生的更大变异性。
