Abstract:
Living organisms routinely navigate their surroundings in search of better conditions, more food, or to avoid predators. Typically, animals do so by integrating sensory cues from the environment with their locomotor apparatuses. For single cells or small organisms that possess motility, fundamental physical constraints imposed by their small size have led to alternative navigation strategies that are specific to the microscopic world. Intriguingly, underlying these myriad exploratory behaviours or sensory functions is the onset of periodic activity at multiple scales, such as the undulations of cilia and flagella, the vibrations of hair cells, or the oscillatory shape modes of migrating neutrophils. Here, I explore oscillatory dynamics in basal microeukaryotes and hypothesize that these active oscillations play a critical role in enhancing the fidelity of adaptive sensorimotor integration.
摘要:
活的有机体经常在他们的周围环境中寻找更好的条件,更多的食物,或避免捕食者。通常,动物通过将来自环境的感觉线索与它们的运动设备整合来做到这一点。对于具有运动性的单细胞或小生物,它们的小尺寸所施加的基本物理约束导致了针对微观世界的替代导航策略。有趣的是,这些无数的探索行为或感觉功能的基础是多个尺度的周期性活动的开始,比如纤毛和鞭毛的起伏,毛细胞的振动,或中性粒细胞迁移的振荡形状模式。这里,我探索了基础微真核生物中的振荡动力学,并假设这些主动振荡在增强自适应感觉运动整合的保真度中起着关键作用。