PDF(Pubmed)
Abstract：
BACKGROUND: Adenoid cystic carcinoma (ACC) of orbit is a very rare epithelial tumor, often originating from the lacrimal glands. At the same time, treatment options are currently limited, such as radiation, chemotherapy. We report a case of a patient treated with antirotinib combined with radiotherapy.
METHODS: A 13-year-old girl was initially admitted with \"left eye swelling for over half a year, 12 days after surgery for left orbital adenoid cystic carcinoma\". Initial swelling of the lateral upper eyelid of the left eye, with gradual enlargement and occasional pain.
METHODS: Left orbital adenoid cystic carcinoma.
METHODS: After diagnosis of orbital ACC, she underwent resection of the left orbital mass, and received 33 times of adjuvant radiotherapy, but brain metastases appeared later. She refused further treatment, and received 25 times of radiotherapy and anlotinib therapy after the disease progressed again.
RESULTS: Now the patient has been followed up for 8 months, but no progress was found.
CONCLUSIONS: Based on this, we hypothesized that radiation therapy in combination with anlotinib is effective for ACC or ACC metastases.
METHODS: A 13-year-old girl was initially admitted with \"left eye swelling for over half a year, 12 days after surgery for left orbital adenoid cystic carcinoma\". Initial swelling of the lateral upper eyelid of the left eye, with gradual enlargement and occasional pain.
METHODS: Left orbital adenoid cystic carcinoma.
METHODS: After diagnosis of orbital ACC, she underwent resection of the left orbital mass, and received 33 times of adjuvant radiotherapy, but brain metastases appeared later. She refused further treatment, and received 25 times of radiotherapy and anlotinib therapy after the disease progressed again.
RESULTS: Now the patient has been followed up for 8 months, but no progress was found.
CONCLUSIONS: Based on this, we hypothesized that radiation therapy in combination with anlotinib is effective for ACC or ACC metastases.
摘要：
背景：眼眶腺样囊性癌（ACC）是一种非常罕见的上皮性肿瘤，通常起源于泪腺。同时,目前治疗方案有限，如辐射，化疗。我们报告了一例使用抗罗替尼联合放疗治疗的患者。
方法：一名13岁女孩最初因左眼肿胀而入院半年以上，左眶腺样囊性癌手术后12天。”左眼外侧上眼睑的初始肿胀，逐渐扩大，偶尔疼痛。
方法：左眶腺样囊性癌。
方法：诊断眼眶ACC后，她接受了左眶肿块的切除,接受了33次辅助放疗，但后来出现脑转移。她拒绝进一步治疗,病情再次进展后接受25次放疗和安洛替尼治疗。
结果：目前已随访8个月，但没有发现任何进展。
结论：基于此，我们假设放疗联合安洛替尼对ACC或ACC转移有效.
方法：一名13岁女孩最初因左眼肿胀而入院半年以上，左眶腺样囊性癌手术后12天。”左眼外侧上眼睑的初始肿胀，逐渐扩大，偶尔疼痛。
方法：左眶腺样囊性癌。
方法：诊断眼眶ACC后，她接受了左眶肿块的切除,接受了33次辅助放疗，但后来出现脑转移。她拒绝进一步治疗,病情再次进展后接受25次放疗和安洛替尼治疗。
结果：目前已随访8个月，但没有发现任何进展。
结论：基于此，我们假设放疗联合安洛替尼对ACC或ACC转移有效.
