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Abstract：
Radiotherapy (RT) is a fundamental modality in treatment of cervical cancer. With advancement of technology, conventional RT used for external beam radiotherapy (EBRT) for over half a century has been rapidly replaced with intensity-modulated radiation therapy (IMRT) especially during the last decade. This newer technique is able to differentiate the intensity of radiation within the same field, thus reduces the inevitable exposure of radiation to normal organs and enables better dose delivery to tumors. Recently, the American Society for Radiation Oncology has released a guideline for RT in cervical cancer. Although a section of the guideline recommends IMRT for the purpose of toxicity reduction, a thorough review of the literature is necessary to understand the current status of IMRT in cervical cancer. This narrative review updates the recent high-level evidences regarding the efficacy and toxicity of IMRT and provides a better understanding of the most innovative techniques currently available for EBRT enabled by IMRT.
摘要：
放射治疗（RT）是宫颈癌治疗的基本方法。随着技术的进步,半个多世纪以来，用于外束放射治疗（EBRT）的常规RT已被强度调节放射治疗（IMRT）迅速取代，尤其是在过去的十年中。这种新技术能够区分同一场内的辐射强度，因此减少了辐射对正常器官的不可避免的暴露，并能够更好地将剂量传递给肿瘤。最近,美国放射肿瘤学会发布了宫颈癌放疗指南.尽管指南的一部分建议IMRT以减少毒性为目的，有必要对文献进行全面回顾,以了解宫颈癌IMRT的现状.这篇叙述性综述更新了有关IMRT的疗效和毒性的最新高水平证据，并提供了对IMRT启用的当前可用于EBRT的最具创新性技术的更好理解。
